Evidence map›Paper›PMID 35568789›Full record

ReviewMolecular biology reports2022

CRISPR/Cas technology for improving nutritional values in the agricultural sector: an update.

Mayank Chaudhary, Tapan Kumar Mukherjee, Raj Singh, Mahiti Gupta, Soniya Goyal, Paavan Singhal, Rakesh Kumar, Nabin Bhusal, Pooja Sharma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Mayank ChaudharyDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, 133207, India.
Tapan Kumar MukherjeeDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, 133207, India.
Raj SinghDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, 133207, India.
Mahiti GuptaDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, 133207, India.
Soniya GoyalDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, 133207, India.
Paavan SinghalDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, 133207, India.
Rakesh KumarInstitute for Cereal Crops Improvement, Tel Aviv University, Tel Aviv, Israel.
Nabin BhusalDepartment of Genomics and Plant Breeding, Agriculture and Forestry University, Rampur, Chitwan, Nepal.
Pooja SharmaDepartment of Biotechnology, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, 133207, India. pooja0029@gmail.com.ORCID http://orcid.org/0000-0002-0387-9669
Maharishi Markandeshwar University, Mullana · INAgriculture and Forestry University · NPTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) system was initially identified in bacteria and archaea as a defense mechanism to confer immunity against phages. Later on, it was developed as a gene editing tool for both prokaryotic and eukaryotic cells including plant cells. METHODS AND

resultsCRISPR/Cas9 approach has wider applications in reverse genetics as well as in crop improvement. Various characters involved in enhancing economic value and crop sustainability against biotic/abiotic stresses can be targeted through this tool. Currently, CRISPR/Cas9 gene editing mechanism has been applied on around 20 crop species for improvement in several traits including yield enhancement and resistance against biotic and abiotic stresses. In the last five years, maximum genome editing research has been validated in rice, wheat, maize and soybean. Genes targeted in these plants has been involved in causing male sterility, conferring resistance against pathogens or having certain nutritional value.

conclusionsCurrent review summarizes various applications of CRISPR/Cas system and its future prospects in plant biotechnology targeting crop improvement with higher yield, disease tolerance and enhanced nutritional value.

Indexed as

CRISPR-Cas SystemsCrops, AgriculturalBiotechnologyGenome, PlantNutritive ValuePlants, Genetically ModifiedAbiotic stressBiotic stressCas9CRISPRCrop improvementGenome editing

Identifiers

PMID35568789
OpenAlexW4280523961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.