Evidence map›Paper›PMID 35568747›Full record

ReviewMedical oncology (Northwood, London, England)2022

The functions, oncogenic roles, and clinical significance of circular RNAs in renal cell carcinoma.

Hui Huang, Tao Chen, Fei Li, Dan Jin, Chuan Li, Yongbo Yang, Xuyang Liu, Dongmiao Wang, Jiehui Di

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hui Huang *Department of Oncology, Kaizhou District People's Hospital of Chongqing, Chongqing, China.
Tao Chen *Department of Osteology, Kaizhou District People's Hospital of Chongqing, Chongqing, China.
Fei LiDepartment of Osteology, Kaizhou District People's Hospital of Chongqing, Chongqing, China.
Dan JinDepartment of Oncology, Kaizhou District People's Hospital of Chongqing, Chongqing, China.
Chuan LiDepartment of Oncology, Kaizhou District People's Hospital of Chongqing, Chongqing, China.
Yongbo YangDepartment of Oncology, Kaizhou District People's Hospital of Chongqing, Chongqing, China.
Xuyang LiuDepartment of Oncology, Kaizhou District People's Hospital of Chongqing, Chongqing, China.
Dongmiao WangDepartment of Oncology, Kaizhou District People's Hospital of Chongqing, Chongqing, China. wdmm965@163.com.
Jiehui DiCancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China. djh@xzhmu.edu.cn.ORCID http://orcid.org/0000-0002-3806-2915
People's Hospital of Kaizhou District · CNJiangsu University · CN

Funding

national natural science foundation of china 81972377
6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is the most common form of malignancy affecting the kidneys. Circular RNAs (circRNAs) are non-coding RNAs that are derived from exonic or intronic sequences through a selective shearing process. There is growing evidence that these circRNAs can influence a range of biological pathways by serving as protein decoys, microRNA sponges, regulators of transcriptional activity, or templates for protein translation. The dysregulation of circRNA expression patterns is a hallmark of RCC and other cancer types, and there is strong evidence that these RNA species can play central roles in the onset and progression of RCC tumors. In the present review, we summarized recent findings on the functional roles and clinical impacts of circRNAs in RCC. Further, we discussed their potential utility as diagnostic biomarkers or targets for therapeutic intervention.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsMicroRNAsCarcinogenesisHumansRNA, CircularMicroRNAsRNA, CircularBiological functioncircRNARenal cell carcinomaSignalingTherapeutic targets

Identifiers

PMID35568747
OpenAlexW4280512783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.