ReviewAmerican journal of obstetrics and gynecology2022
COVID-19 vaccination in pregnancy.
Review in American journal of obstetrics and gynecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Quantitative Benefit-Risk Assessment of Vaccination Against COVID-19: A Systematic Review.Pharmacoepidemiology and drug safety · 2025Pooled it
- Immunogenicity and reactogenicity of heterologous COVID-19 vaccination in pregnant women.Human vaccines & immunotherapeutics · 2023Trial
- Effectiveness of oseltamivir in hospitalised obstetric patients with COVID-19: a retrospective cohort study using a Brazilian national database.BMC infectious diseases · 2025Article
- Vaccinations for Expecting Mothers to Improve Pregnancy Care in Middle Tennessee.Pathogens (Basel, Switzerland) · 2025Article
- COVID-19 Vaccination Rates and Vaccine Hesitancy in Pregnant Women in Seven Low- and Middle-Income Countries Through May 2023: An Observational Study From the Global Network.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Monitoring the safety of the adjuvanted human papillomavirus vaccine, HPV-16/18-AS04: Protocol for a cohort study using electronic health records in Yinzhou, China.Human vaccines & immunotherapeutics · 2024Article
- Association of maternal infection of SARS-CoV-2 and neonatal susceptibility: A retrospective cohort study.Vaccine: X · 2024Article
- Transplacental Transmission of SARS-CoV-2: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024Review
- Pathogenesis of viral infections during pregnancy.Clinical microbiology reviews · 2024Review
- COVID-19 Vaccination and Reproductive Health: a Comprehensive Review for Healthcare Providers.Reproductive sciences (Thousand Oaks, Calif.) · 2024Review
- Determinants of Non-Acceptance of the COVID-19 Vaccine During Pregnancy in Pregnant and Postpartum Women: A Descriptive Cross-Sectional Study.Journal of family & reproductive health · 2024Article
- A prospective cohort study of preconception COVID-19 vaccination and miscarriage.Human reproduction (Oxford, England) · 2023Article
- Maternal and perinatal outcomes of COVID-19 vaccination during pregnancy.Journal of the Turkish German Gynecological Association · 2023Article
- Cord blood antibodies following BBIBP-CorV (Sinopharm) vaccination during pregnancy.Immunity, inflammation and disease · 2023Article
- COVID-19 mRNA vaccination status and concerns among pregnant women in Japan: a multicenter questionnaire survey.BMC pregnancy and childbirth · 2023Article
- An Update on COVID-19 Vaccination and Pregnancy.Journal of personalized medicine · 2023Review
- Reductions in stillbirths and preterm birth in COVID-19-vaccinated women: a multicenter cohort study of vaccination uptake and perinatal outcomes.American journal of obstetrics and gynecology · 2023Article
- Immune Response and Transplacental Antibody Transfer in Pregnant Women after COVID-19 Vaccination.Journal of personalized medicine · 2023Article
- Pregnancy Outcomes, Immunophenotyping and Immunohistochemical Findings in a Cohort of Pregnant Patients with COVID-19-A Prospective Study.Diagnostics (Basel, Switzerland) · 2023Article
- The type of SARS-CoV-2 vaccine does not affect ovarian function in assisted reproduction cycle.Fertility and sterility · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite a recent endorsement from official and professional bodies unequivocally recommending COVID-19 vaccination, vaccine hesitancy among pregnant people remains high. The accumulated evidence demonstrates that pregnant people are a special risk group for COVID-19, with an increased risk of intensive care unit admission, extracorporeal membranous oxygenation requirement, preterm birth, and perinatal death. These risks are further increased with some variants of concern, and vaccination of pregnant people reduces the COVID-19-related increase in maternal or fetal morbidity. Data from more than 180,000 vaccinated persons show that immunization against COVID-19 with an mRNA vaccine is safe for pregnant people. Many observational studies comparing perinatal outcomes between vaccinated and unvaccinated pregnant people have had reassuring findings and did not demonstrate harmful effects on pregnancy or the newborn. Immunization with mRNA vaccines does not increase the risk of miscarriage, preterm delivery, low birthweight, maternal or neonatal intensive care unit admission, fetal death, fetal abnormality, or pulmonary embolism. Moreover, observational data corroborate the findings of randomized trials that mRNA vaccination is highly effective at preventing severe SARS-CoV-2 infection in pregnant people, emphasizing that the potential maternal and fetal benefits of vaccination greatly outweigh the potential risks of vaccination. Ensuring pregnant people have unrestricted access to COVID-19 vaccination should be a priority in every country worldwide.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.