Evidence map›Paper›PMID 35568146›Full record

ArticleMechanisms of ageing and development2022

Association between vitamin D status and physical performance in COVID-19 survivors: Results from the Gemelli against COVID-19 post-acute care project.

Vincenzo Galluzzo, Francesca Ciciarello, Matteo Tosato, Maria Beatrice Zazzara, Cristina Pais, Giulia Savera, Riccardo Calvani, Anna Picca, Emanuele Marzetti, Francesco Landi and 1 more

Open access · greenAbstract read
In one paragraph

Article in Mechanisms of ageing and development, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
  8. Malnutrition in COVID-19 survivors: prevalence and risk factors.Aging clinical and experimental research · 2023
    Article
  9. Low Vitamin D Levels Are Associated With Long COVID Syndrome in COVID-19 Survivors.The Journal of clinical endocrinology and metabolism · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Vincenzo GalluzzoFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Francesca CiciarelloFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Matteo TosatoFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Maria Beatrice ZazzaraFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Cristina PaisFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Giulia SaveraFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Riccardo CalvaniFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy. Electronic address: riccardo.calvani@policlinicogemelli.it.
Anna PiccaFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
Emanuele MarzettiFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy; Department of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, Rome, Italy.
Francesco LandiFondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy; Department of Geriatrics and Orthopedics, Università Cattolica del Sacro Cuore, Rome, Italy.
Gemelli Against COVID-19 Post-Acute Care Team
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the prevalence and associated factors of vitamin D deficiency in COVID-19 survivors and the relationship between vitamin D status and physical performance.

methodsVitamin D status was assessed in a sample of patients who had recovered from COVID-19 and were admitted to a post-acute outpatient service at the Fondazione Policlinico Universitario Agostino Gemelli IRCCS (Rome, Italy). Participants were offered comprehensive medical assessment, including physical performance and muscle strength tests. Self-rated health was assessed. Vitamin D deficiency was defined as a serum concentration of 25-OH vitamin D < 20 ng/mL.

resultsMean age of 681 participants was 53.4 ± 15.2 years and 49% were women. Vitamin D deficiency was detected in 35.6% of the whole study population, and in 40.2% of those 65 and older. Vitamin D deficiency was associated with diabetes, higher body mass index, and COVID-19 severity, and showed a seasonal pattern with a peak in autumn/winter. Participants with vitamin D deficiency performed poorer on the six-minute walking test, with the lowest performance observed in those 65 and older. No significant associations with any other parameters were found.

conclusionOur findings indicate that vitamin D deficiency is frequent in COVID-19 survivors, especially in older adults. Low vitamin D levels are associated with poor physical performance, in particular in old age.

Indexed as

COVID-19Vitamin D DeficiencyAgedFemaleHumansMalePhysical Functional PerformanceSubacute CareSurvivorsVitamin DVitamin DAgingExercise toleranceGeriatricsPhysical performanceSix-minute walking test

Identifiers

PMID35568146
PMCPMC9093083
OpenAlexW4280607774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.