Evidence map›Paper›PMID 35567732›Full record

ArticleLa Radiologia medica2022

The value of ultrasound and magnetic resonance imaging scoring systems in explaining handgrip strength and functional impairment in rheumatoid arthritis patients: a pilot study.

Fausto Salaffi, Marina Carotti, Marco Di Carlo, Luca Ceccarelli, Sonia Farah, Andrea Giovagnoni

Open access · hybridAbstract read
In one paragraph

Article in La Radiologia medica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fausto SalaffiRheumatology Clinic, Dipartimento Di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ospedale "Carlo Urbani", Jesi (Ancona), Italy.ORCID http://orcid.org/0000-0002-3794-6831
Marina CarottiDipartimento di Scienze Radiologiche, Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy.ORCID http://orcid.org/0000-0001-6562-180X
Marco Di CarloRheumatology Clinic, Dipartimento Di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ospedale "Carlo Urbani", Jesi (Ancona), Italy. dica.marco@yahoo.it.ORCID http://orcid.org/0000-0002-0906-4647
Luca CeccarelliDepartment of Interventional and Diagnostic Radiology, Azienda Ospedaliero-Universitaria Sant'Anna, Ferrara, Italy.ORCID http://orcid.org/0000-0002-0510-0970
Sonia FarahRheumatology Clinic, Dipartimento Di Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Ospedale "Carlo Urbani", Jesi (Ancona), Italy.ORCID http://orcid.org/0000-0002-9815-2621
Andrea GiovagnoniDipartimento di Scienze Radiologiche, Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy.ORCID http://orcid.org/0000-0002-5264-652X
Marche Polytechnic University · ITArcispedale Sant'Anna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe goal of this study is to investigate the relationship between joint inflammation and damage of the wrists and hands, measured by semiquantitative ultrasound and magnetic resonance imaging scoring systems, with functional disability and handgrip strength (HGs). MATERIALS AND

methodsConsecutive adult RA patients with active disease, as defined by a Disease Activity Score 28 joints C-reactive protein (DAS28-CRP) > 3.2, underwent a cross-sectional evaluation comprehensive of a clinimetric assessment, an HGs evaluation, an ultrasound assessment aimed at calculating the UltraSound-CLinical ARthritis Activity (US-CLARA), and a magnetic resonance imaging scored according to the modified Simplified Rheumatoid Arthritis Magnetic Resonance Imaging Score (mod SAMIS). The Spearman's rho correlation coefficient was used to test the correlations.

resultsSixty-six patients with RA were investigated (age 55.6 ± 12.2 years). The mod SAMIS total score and the US-CLARA had a weak but significant correlation (rho = 0.377, p = 0.0018). Among the mod SAMIS sub-scores, there was a significant relationship between mod SAMIS bone edema (SAMIS-BME) and US-CLARA (rho = 0.799, p < 0.001) and mod SAMIS synovitis (SAMIS synovitis) and US-CLARA (rho = 0.539, p < 0.001). There were also significant negative relationships between the HGs score and the mod SAMIS total score and US-CLARA (rho = - 0.309, p = 0.011 and rho = - 0.775, p < 0.0001, respectively).

conclusionsBME and synovitis have an influence on the function of the upper extremities. The US-CLARA and the mod SAMIS total score are intriguing options for semiquantitative assessment of joint inflammation and damage in RA.

Indexed as

Arthritis, RheumatoidSynovitisAdultAgedCross-Sectional StudiesHand StrengthHumansInflammationMagnetic Resonance ImagingMiddle AgedPilot ProjectsSeverity of Illness IndexDisease activityHandgrip strengthMagnetic resonance imagingRheumatoid arthritisUltrasound

Identifiers

PMID35567732
PMCPMC9130172
OpenAlexW4280491153

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.