Evidence map›Paper›PMID 35567639›Full record

ArticleClinical oral investigations2022

Development of root resorption during orthodontic tooth movement after cleft repair using different grafting materials in rats.

Stephan Christian Möhlhenrich, Kristian Kniha, Zuzanna Magnuska, Sachin Chhatwani, Benita Hermanns-Sachweh, Felix Gremse, Frank Hölzle, Gholamreza Danesh, Ali Modabber

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Stephan Christian MöhlhenrichDepartment of Orthodontics, University of Witten/Herdecke, Alfred-Herrhausen Str. 45, 58455, Witten, Germany. stephan.moehlhenrich@uni-wh.de.ORCID http://orcid.org/0000-0002-7023-991X
Kristian KnihaDepartment of Oral and Maxillofacial Surgery, University Hospital of Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Zuzanna MagnuskaInstitute for Experimental Molecular Imaging, Department of Nanomedicine and Theragnostic, RWTH Aachen University, Forckenbeckstraße 55, 52074, Aachen, Germany.
Sachin ChhatwaniDepartment of Orthodontics, University of Witten/Herdecke, Alfred-Herrhausen Str. 45, 58455, Witten, Germany.
Benita Hermanns-SachwehImplant Pathology, ZBMT, Campus Melaten, Pauwelsstraße 17, 52074, Aachen, Germany.
Felix GremseInstitute for Experimental Molecular Imaging, Department of Nanomedicine and Theragnostic, RWTH Aachen University, Forckenbeckstraße 55, 52074, Aachen, Germany.
Frank HölzleDepartment of Oral and Maxillofacial Surgery, University Hospital of Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Gholamreza DaneshDepartment of Orthodontics, University of Witten/Herdecke, Alfred-Herrhausen Str. 45, 58455, Witten, Germany.
Ali ModabberDepartment of Oral and Maxillofacial Surgery, University Hospital of Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Universitätsklinikum Aachen · DEWitten/Herdecke University · DERWTH Aachen University · DE

Funding

Medizinische Fakultät, RWTH Aachen University Grant No. 104/18
6 · The paper itself

Abstract

objectiveThe aim of the present study was to investigate the influence of three grafting materials for cleft repair on orthodontic tooth movement in rats. MATERIALS AND

methodsArtificial alveolar clefts were created in 21 Wistar rats and were repaired 4 weeks later using autografts, human xenografts and synthetic bone substitute (beta-tricalcium phosphate/hydroxyapatite [β-TCP/HA]). A further 4 weeks later, the first molar was moved into the reconstructed maxilla. Microfocus computed tomography (μCT) was performed six times (T0-T5) to assess the tooth movement and root resorption. After 8 weeks, the affected reconstructed jaw was resected for histopathological investigation.

resultsTotal distances reached ranged from 0.82 ± 0.72 mm (β-TCP/HA) to 0.67 ± 0.27 mm (autograft). The resorption was particularly determined at the mesiobuccal root. Descriptive tooth movement slowed and root resorption increased slightly. However, neither the radiological changes during tooth movement (µCT T1 vs. µCT T5: autograft 1.85 ± 0.39 mm

conclusionThe autografts, human xenografts or synthetic bone substitute used for cleft repair seem to have a similar effect on the subsequent orthodontic tooth movement and the associated root resorptions. CLINICAL RELEVANCE: Development of root resorptions seems to have a secondary role in choosing a suitable grafting material for cleft repair.

Indexed as

Bone SubstitutesRoot ResorptionAnimalsCalcium PhosphatesHumansRatsRats, WistarTooth Movement TechniquesTooth Rootbeta-tricalcium phosphateBone SubstitutesCalcium PhosphatesCleft palateCleft repairGrafting materialsJaw reconstructionRoot resorptionTooth movement

Identifiers

PMID35567639
PMCPMC9474460
OpenAlexW4280510549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.