Evidence map›Paper›PMID 35567425›Full record

SynthesisInternational wound journal2023

Association between vitamin D deficiency and diabetic foot ulcer wound in diabetic subjects: A meta-analysis.

Juan Lin, Xinxin Mo, Yejun Yang, Chao Tang, Jia Chen

RetractedOpen access · goldAbstract readMeta-AnalysisRetracted Publication
In one paragraph

Synthesis in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Micronutrient status of patients with diabetic foot: A systematic review.Asia Pacific journal of clinical nutrition · 2025
    Pooled it
  2. Pooled it
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  5. Review
  6. Article
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  10. Review
  11. Signaling pathways in cutaneous wound healing.Frontiers in physiology · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Juan LinNursing School of Shaoyang University, Hunan, China.
Xinxin MoNursing School of Shaoyang University, Hunan, China.
Yejun YangDepartment of Pediatric, Shaoyang Central Hospital, Hunan, China.
Chao TangNursing School of Shaoyang University, Hunan, China.
Jia ChenXiangya School of Nursing School of Central South University, Hunan, China.ORCID https://orcid.org/0000-0003-2465-9443
Shaoyang University · CNCentral South University · CNThe Central Hospital of Shaoyang · CN

Funding

Hunan Education Department 20C1673Shaoyang Federation of Social Science 21YBB39
6 · The paper itself

Abstract

A meta-analysis was performed to evaluate the association between vitamin D deficiency and diabetic foot ulcer wounds in diabetic subjects. A systematic literature search up to March 2022 incorporated 7586 subjects with diabetes mellitus at the beginning of the study; 1565 were using diabetic subjects with foot ulcer wounds, and 6021 were non-ulcerated diabetic subjects. Statistical tools like the dichotomous and contentious method were used within a random or fixed-influence model to establish the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) to evaluate the influence of vitamin D deficiency in managing diabetic foot ulcer wound. Diabetic subjects with foot ulcer wounds had significantly lower vitamin D levels (MD, -6.48; 95% CI, -10.84 to -2.11, P < .004), higher prevalence of vitamin D deficiency (<50 nmoL/L) (OR, 1.82; 95% CI, 1.32-2.52, P < .001), and higher prevalence of severe vitamin D deficiency (OR, 2.53; 95% CI, 1.65-3.89, P < .001) compared with non-ulcerated diabetic subjects. Diabetic subjects with foot ulcer wounds had significantly lower vitamin D levels, higher prevalence of vitamin D deficiency, and higher prevalence of severe vitamin D deficiency compared with non-ulcerated diabetic subjects. Further studies are required to validate these findings.

Indexed as

Diabetes MellitusDiabetic FootFoot UlcerVitamin D DeficiencyHumansVitamin DVitamin Ddiabetic foot ulcer woundseverethe prevalence of vitamin D deficiencyvitamin D deficiencyvitamin D levels

Identifiers

PMID35567425
PMCPMC9797924
OpenAlexW4280567223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.