Evidence map›Paper›PMID 35566897›Full record

ArticlePolymers2022

Development and Preclinical Investigation of Physically Cross-Linked and pH-Sensitive Polymeric Gels as Potential Vaginal Contraceptives.

Ankit Rochani, Vivek Agrahari, Neelima Chandra, Onkar N Singh, Timothy J McCormick, Gustavo F Doncel, Meredith R Clark, Gagan Kaushal

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ankit RochaniDepartment of Pharmaceutical Science, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Vivek AgrahariCONRAD, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Neelima ChandraCONRAD, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Onkar N SinghCONRAD, Eastern Virginia Medical School, Norfolk, VA 23507, USA.ORCID 0000-0002-3386-7300
Timothy J McCormickCONRAD, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Gustavo F DoncelCONRAD, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Meredith R ClarkCONRAD, Eastern Virginia Medical School, Norfolk, VA 23507, USA.ORCID 0000-0002-4476-8287
Gagan KaushalDepartment of Pharmaceutical Science, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Eastern Virginia Medical School · USThomas Jefferson University · US

Funding

Bill & Melinda Gates Foundation OPP1162284
6 · The paper itself

Abstract

This study explored the development of cross-linked gels to potentially provide a physical barrier to vaginal sperm transport for contraception. Two types of gels were formulated, a physically cross-linked iota-carrageenan (C

Indexed as

contraceptive formulationcross-linked gelphysical barrierrheologyvaginal sperm transport

Identifiers

PMID35566897
PMCPMC9101208
OpenAlexW4224314824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.