Evidence map›Paper›PMID 35566847›Full record

ArticlePolymers2022

Biocompatible Nanoparticles Based on Amphiphilic Random Polypeptides and Glycopolymers as Drug Delivery Systems.

Natalia Zashikhina, Mariia Levit, Anatoliy Dobrodumov, Sergey Gladnev, Antonina Lavrentieva, Tatiana Tennikova, Evgenia Korzhikova-Vlakh

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Natalia ZashikhinaInstitute of Macromolecular Compounds, Russian Academy of Sciences, Bolshoy pr. 31, 199004 St. Petersburg, Russia.ORCID 0000-0002-3039-1327
Mariia LevitInstitute of Macromolecular Compounds, Russian Academy of Sciences, Bolshoy pr. 31, 199004 St. Petersburg, Russia.
Anatoliy DobrodumovInstitute of Macromolecular Compounds, Russian Academy of Sciences, Bolshoy pr. 31, 199004 St. Petersburg, Russia.ORCID 0000-0002-4554-6002
Sergey GladnevInstitute of Chemistry, Saint-Petersburg State University, Universitesky pr. 26, 198504 St. Petersburg, Russia.
Antonina LavrentievaInstitute of Technical Chemistry, Gottfried-Wilhelm-Leibniz University of Hannover, 30167 Hannover, Germany.ORCID 0000-0003-0003-5572
Tatiana TennikovaInstitute of Chemistry, Saint-Petersburg State University, Universitesky pr. 26, 198504 St. Petersburg, Russia.ORCID 0000-0002-9029-2056
Evgenia Korzhikova-VlakhInstitute of Macromolecular Compounds, Russian Academy of Sciences, Bolshoy pr. 31, 199004 St. Petersburg, Russia.ORCID 0000-0002-2530-7709
Institute of Macromolecular Compounds · RUSt Petersburg University · RULeibniz University Hannover · DE

Funding

Russian Foundation for Basic Research 18-33-01018Russian Science Foundation 20-73-00222
6 · The paper itself

Abstract

In this research, the development and investigation of novel nanoobjects based on biodegradable random polypeptides and synthetic non-degradable glycopolymer poly(2-deoxy-2-methacrylamido-d-glucose) were proposed as drug delivery systems. Two different approaches have been applied for preparation of such nanomaterials. The first one includes the synthesis of block-random copolymers consisting of polypeptide and glycopolymer and capable of self-assembly into polymer particles. The synthesis of copolymers was performed using sequential reversible addition-fragmentation chain transfer (RAFT) and ring-opening polymerization (ROP) techniques. Amphiphilic poly(2-deoxy-2-methacrylamido-d-glucose)-b-poly(l-lysine-

Indexed as

amphiphilic copolymerscellular uptake of particlesdrug delivery systemspolymer particlespolypeptidesrandom and block-random copolymerssynthetic glycopolymers

Identifiers

PMID35566847
PMCPMC9104652
OpenAlexW4224231317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.