Evidence map›Paper›PMID 35566760›Full record

ArticleJournal of clinical medicine2022

Increased Plasma Lipocalin-2 Levels in Patients with Myelin Oligodendrocyte Glycoprotein-IgG-Positive Optic Neuritis.

Jong-Heon Kim, Hyejin Lee, Junho Oh, Kyoungho Suk, Bo Young Chun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jong-Heon KimBrain Science & Engineering Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Hyejin LeeDepartment of Ophthalmology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Junho OhDepartment of Ophthalmology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Kyoungho SukBrain Science & Engineering Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.ORCID 0000-0002-9555-4203
Bo Young ChunBrain Science & Engineering Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Kyungpook National University · KR

Funding

Biomedical Research Institute Grant, Kyungpook National University Hospital 2018
6 · The paper itself

Abstract

This study aimed to evaluate the correlation between plasma lipocalin-2 (LCN2) levels and myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G (IgG) seropositivity in patients with optic neuritis. Peripheral blood samples were collected from 19 patients with optic neuritis and 20 healthy controls. Plasma LCN2 and MOG-IgG levels were measured using enzyme-linked immunosorbent assay and a cell-based assay, respectively. The correlation between plasma LCN2 levels and MOG-IgG titers in patients with optic neuritis was analyzed. Receiver operating characteristic (ROC) curves were constructed to assess and compare the ability of plasma LCN2 and MOG-IgG levels for predicting optic neuritis recurrence. Patients with MOG-IgG-positive optic neuritis had significantly higher mean plasma LCN2 levels than controls and patients with MOG-IgG-negative optic neuritis (

Indexed as

lipocalin-2myelin oligodendrocyte glycoprotein IgGoptic neuritisrecurrence

Identifiers

PMID35566760
PMCPMC9105342
OpenAlexW4229331898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.