Evidence map›Paper›PMID 35566758›Full record

ArticleJournal of clinical medicine2022

Acute Pulmonary Artery Thrombosis despite Anticoagulation in Patients with COVID-19 Pneumonia: A Single-Center Retrospective Cohort Study.

Cristian-Mihail Niculae, Ana-Maria-Jennifer Anghel, Eliza-Daniela Militaru, Laura-Georgiana Tîrlescu, Mihai Lazar, Adriana Hristea

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cristian-Mihail NiculaeInfectious Diseases Department, Faculty of Medicine, University of Medicine and Pharmacy "Carol Davila", No. 37, Dionisie Lupu Street, Sector 2, 020021 Bucharest, Romania.ORCID 0000-0001-6359-238X
Ana-Maria-Jennifer AnghelNational Institute for Infectious Diseases "Prof. Dr. Matei Bals", No. 1, Calistrat Grozovici Street, Sector 2, 021105 Bucharest, Romania.
Eliza-Daniela MilitaruInfectious Diseases Department, Faculty of Medicine, University of Medicine and Pharmacy "Carol Davila", No. 37, Dionisie Lupu Street, Sector 2, 020021 Bucharest, Romania.
Laura-Georgiana TîrlescuNational Institute for Infectious Diseases "Prof. Dr. Matei Bals", No. 1, Calistrat Grozovici Street, Sector 2, 021105 Bucharest, Romania.ORCID 0000-0001-8283-0689
Mihai LazarInfectious Diseases Department, Faculty of Medicine, University of Medicine and Pharmacy "Carol Davila", No. 37, Dionisie Lupu Street, Sector 2, 020021 Bucharest, Romania.ORCID 0000-0002-1169-3653
Adriana HristeaInfectious Diseases Department, Faculty of Medicine, University of Medicine and Pharmacy "Carol Davila", No. 37, Dionisie Lupu Street, Sector 2, 020021 Bucharest, Romania.ORCID 0000-0002-6505-1699
Carol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: We aimed to describe the clinical and imaging characteristics of patients diagnosed with pulmonary artery thrombosis (PAT) despite receiving anticoagulation with low-molecular-weight heparin (LMWH). (2) Methods: We retrospectively studied all hospitalized COVID-19 adult patients diagnosed with PAT between March 2020 and December 2021, who received LMWH for ≥72 h until the diagnosis of PAT. Acute PAT was confirmed by a CT pulmonary angiogram. (3) Results: We included 30 severe and critical COVID-19 patients. Median age was 62 (54-74) years, with 83.3% males, and comorbidities seen in 73.3%. PAT was diagnosed despite prophylactic (23.3%), intermediate (46.6%) or therapeutic (30%) doses of LMWH for a median time of 8 (4.7-12) days. According to their Wells score, 80% of patients had a low probability of pulmonary embolism diagnosis. PAT was localized in the lower lobes of the lungs in 76.6% of cases with 33.3% having bilateral involvement, with the distal, peripheral arteries being the most affected. At the PAT diagnosis we found a worsening of respiratory function, with seven patients progressing to mechanical ventilation (

Indexed as

anticoagulationCOVID-19pulmonary artery thrombosispulmonary embolism

Identifiers

PMID35566758
PMCPMC9100155
OpenAlexW4229336161

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.