ArticleJournal of clinical medicine2022
Improving Upper Extremity Bradykinesia in Parkinson's Disease: A Randomized Clinical Trial on the Use of Gravity-Supporting Exoskeletons.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 6 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- The Effects of Digital Health Interventions on Motor Symptoms, Nonmotor Symptoms, and Quality of Life in Patients With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Comparative effects and dose-response relationships of exercise for finger dexterity and upper-limb function in Parkinson's disease: a Bayesian network and model-based dose-response meta-analysis.Frontiers in neurology · 2026Pooled it
- Standardized clinical assessments and advanced AI-driven instruments used to evaluate neurofunctional deficits, including within biomarker based framework, in Parkinson's disease - human intelligence made vs. AI models - systematic review.Frontiers in medicine · 2025Pooled it
- Effectiveness of robot-assisted training in adults with Parkinson's disease: a systematic review and meta-analysis.Journal of neurology · 2024Pooled it
- The Effectiveness of Inpatient Rehabilitation in Parkinson's Disease: A Systematic Review of Recent Studies.Journal of Parkinson's disease · 2024Pooled it
- Type, Timing, Frequency, and Durability of Outcome of Physical Therapy for Parkinson Disease: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Effects of robotic hand-assisted rehabilitation on motor function and daily living activities in acute stroke: a randomized controlled trial.Scientific reports · 2026Trial
- Effects of a gait training program with the FisiorBMC complementary medicine and therapies · 2026Trial
- AGREE: an upper limb motorized exoskeleton for restoring arm functions: a single-blinded randomized controlled trial.Journal of neuroengineering and rehabilitation · 2025Trial
- The effects of exergames on upper extremity performance, trunk mobility, gait, balance, and cognition in Parkinson's disease: a randomized controlled study.Acta neurologica Belgica · 2024Trial
- A Retrospective Clinical Analysis of Pain and Spasticity Outcomes Following Gravity-Support Exoskeleton Therapy in Chronic Stroke.Journal of clinical medicine · 2026Article
- Data-driven analysis of Armeo Spring performance across neurological disorders: implications for personalized upper limb neurorehabilitation.Frontiers in robotics and AI · 2026Article
- The effects of robot-assisted arm training on upper limb functions in Parkinson disease.Turkish journal of physical medicine and rehabilitation · 2025Article
- Exploring the Impact of Robotic Hand Rehabilitation on Functional Recovery in Parkinson's Disease: A Randomized Controlled Trial.Brain sciences · 2025Article
- Applications of Near Infrared Spectroscopy and Mirror Therapy for Upper Limb Rehabilitation in Post-Stroke Patients: A Brain Plasticity Pilot Study.Journal of clinical medicine · 2024Article
- Cost analysis of technological vs. conventional upper limb rehabilitation for patients with neurological disorders: an Italian real-world data case study.Frontiers in public health · 2024Article
- Areas of Research Focus and Trends in the Research on the Application of VR in Rehabilitation Medicine.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hand movements are particularly impaired in patients with Parkinson's Disease (PD), contributing to functional disability and difficulties in activities of daily living. Growing evidence has shown that robot-assisted therapy may be considered an effective and reliable method for the delivery of the highly repetitive training that is needed to trigger neuroplasticity, as intensive, repetitive and task-oriented training could be an ideal strategy to facilitate the relearning of motor function and to minimize motor deficit. The purpose of this study is to evaluate the improvement of hand function with semi-autonomous exercises using an upper extremity exoskeleton in patients with PD. A multicenter, parallel-group, randomized clinical trial was then carried out at the IRCCS Centro Neurolesi Bonino-Pulejo (Messina, Italy). Thirty subjects with a diagnosis of PD and a Hoehn-Yahr score between 2 and 3 were enrolled in the study. Patients were 1:1 randomized into either the experimental group (ERT), receiving 45 min training daily, 6 days weekly, for 8 weeks with Armeo
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.