ArticleJournal of clinical medicine2022
Arterial Stiffness Determinants for Primary Cardiovascular Prevention among Healthy Participants.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Effects of exercise on pulse wave velocity in hypertensive and prehypertensive patients: a systematic review and meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2025Pooled it
- Biological aging mediates and frailty modifies the associations of arterial stiffness with incident probable sarcopenia and sarcopenia: a prospective cohort study of UK biobank.Frontiers in public health · 2026Article
- Data-hugging shields proprietary AI models from research that could disprove them.NPJ artificial intelligence · 2026Review
- The arterial stiffness and pulse pressure are predictors of intraocular pressure in a middle-aged population.Scientific reports · 2025Article
- Comparative Analysis of Heart Rate Variability and Arterial Stiffness in Elite Male Athletes after COVID-19.Journal of clinical medicine · 2024Article
- Added value of arterial stiffness index for the 10-year atherosclerotic cardiovascular disease risk determination in a middle-aged population-based study.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Article
- Article
- Association between tobacco smoking and alcohol consumption with arterial stiffness.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Acute and Chronic Effect of Physiological Factors on Arterial Stiffness.Journal of clinical medicine · 2023Article
- Association between Social Isolation and Loneliness with Estimated Atherosclerotic Cardiovascular Disease Risk in a UK Biobank Population-Based Study.International journal of environmental research and public health · 2023Article
- Severe COVID-19-A Review of Suggested Mechanisms Based on the Role of Extracellular Matrix Stiffness.International journal of molecular sciences · 2023Review
- Sex Associations Between Air Pollution and Estimated Atherosclerotic Cardiovascular Disease Risk Determination.International journal of public health · 2023Article
- Arterial stiffness and biological parameters: A decision tree machine learning application in hypertensive participants.PloS one · 2023Article
- Arterial stiffness nomogram identification by cluster analysis: A new approach of vascular phenotype modeling.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- The Correlation of Arterial Stiffness Parameters with Aging and Comorbidity Burden.Journal of clinical medicine · 2022Article
- Sexual behaviors, cannabis, alcohol and monkeypox infection.Frontiers in public health · 2022Review
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1 author at 1 institution in 1 country.
Funding
Abstract
Background: Arterial stiffness (AS), measured by arterial stiffness index (ASI), can be considered as a major denominator in cardiovascular (CV) diseases. Thus, it remains essential to highlight the risk factors influencing its increase among healthy participants. Methods: According to European consensus, AS is defined as ASI > 10 m/s. The purpose of this study was to investigate the determinants of the arterial stiffness (ASI > 10 m/s) among UK Biobank normotensive and healthy participants without comorbidities and previous CV diseases. Thus, a cross-sectional study was conducted on 22,452 healthy participants. Results: Participants were divided into two groups, i.e., ASI > 10 m/s (n = 5782, 25.8%) and ASI < 10 m/s (n = 16,670, 74.2%). All the significant univariate covariables were included in the multivariate analysis. The remaining independent factors associated with AS were age (OR = 1.063, threshold = 53.0 years, p < 0.001), BMI (OR = 1.0450, threshold = 24.9 kg/m2, p < 0.001), cystatin c (OR = 1.384, threshold = 0.85 mg/L, p = 0.011), phosphate (OR = 2.225, threshold = 1.21 mmol/L, p < 0.001), triglycerides (OR = 1.281, threshold = 1.09 mmol/L, p < 0.001), mean BP (OR = 1.028, threshold = 91.2 mmHg, p < 0.001), HR (OR = 1.007, threshold = 55 bpm, p < 0.001), Alkaline phosphate (OR = 1.002, threshold = 67.9 U/L, p = 0.004), albumin (OR = 0.973, threshold = 46.0 g/L, p < 0.001), gender (male, OR = 1.657, p < 0.001) and tobacco use (current, OR = 1.871, p < 0.001). Conclusion: AS is associated with multiple parameters which should be investigated in future prospective studies. Determining the markers of increased ASI among healthy participants participates in the management of future CV risk for preventive strategies.
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