Evidence map›Paper›PMID 35566612›Full record

ReviewJournal of clinical medicine2022

Asian Race and Primary Open-Angle Glaucoma: Where Do We Stand?

Aditya Belamkar, Alon Harris, Francesco Oddone, Alice Verticchio Vercellin, Anna Fabczak-Kubicka, Brent Siesky

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Immunomodulatory and Antioxidant Drugs in Glaucoma Treatment.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Aditya BelamkarDepartment of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID 0000-0003-2247-6942
Alon HarrisDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Francesco OddoneIRCCS-Fondazione Bietti, 00198 Rome, Italy.
Alice Verticchio VercellinDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Anna Fabczak-KubickaDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Brent SieskyDepartment of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Icahn School of Medicine at Mount Sinai · USFondazione G.B. Bietti · ITIndiana University School of MedicineNew York Eye and Ear Infirmary · US

Funding

Integration of clinical measures and theoretical modeling to quantify sectorial specific changes in ocular structure, function, and hemodynamicsR01EY030851 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ARCIERO, JULIA, HARRIS, ALON · 2020 to 2023
$1.3M
National Science Foundation NSF DMS (1853222/2021192)NEI NIH HHS R01 EY030851NIH HHS R01EY030851NYEE Foundation NYEE Foundation grantResearch to Prevent Blindness Challenge Grant award
6 · The paper itself

Abstract

Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by irreversible retinal ganglion cell damage and visual field loss. The global POAG prevalence is estimated to be 3.05%, and near term is expected to significantly rise, especially within aging Asian populations. Primary angle-closure glaucoma disproportionately affects Asians, with up to four times greater prevalence of normal-tension glaucoma reported compared with high-tension glaucoma. Estimates for overall POAG prevalence in Asian populations vary, with Chinese and Indian populations representing the majority of future cases. Structural characteristics associated with glaucoma progression including the optic nerve head, retina, and cornea are distinct in Asians, serving as intermediates between African and European descent populations. Patterns in IOP suggest some similarities between races, with a significant inverse relationship between age and IOP only in Asian populations. Genetic differences have been suggested to play a role in these differences, however, a clear genetic pattern is yet to be established. POAG pathogenesis differs between Asians and other ethnicities, and it may differ within the broad classification of the Asian race. Greater awareness and further research are needed to improve treatment plans and outcomes for the increasingly high prevalence of normal tension glaucoma within aging Asian populations.

Indexed as

Asian populationcorneageneticsglaucomaintraocular pressurenormal tension glaucomaoptic nerve headprimary open angle glaucomaraceretina

Identifiers

PMID35566612
PMCPMC9099679
OpenAlexW4225124546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.