Evidence map›Paper›PMID 35566601›Full record

ArticleJournal of clinical medicine2022

Impact of Preterm Birth on Neurodevelopmental Disorders in South Korea: A Nationwide Population-Based Study.

Jong Ho Cha, Ja-Hye Ahn, Yun Jin Kim, Bong Gun Lee, Johanna Inhyang Kim, Hyun-Kyung Park, Bung-Nyun Kim, Hyun Ju Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jong Ho ChaDepartment of Pediatrics, Hanyang University Hospital, Hanyang University College of Medicine, Seoul 04763, Korea.ORCID 0000-0002-7883-8714
Ja-Hye AhnDepartment of Pediatrics, Hanyang University Hospital, Hanyang University College of Medicine, Seoul 04763, Korea.
Yun Jin KimBiostatistical Consulting and Research Lab, Medical Research Collaborating Center, Hanyang University, Seoul 04763, Korea.ORCID 0000-0003-3202-2696
Bong Gun LeeDepartment of Orthopedic Surgery, Hanyang University Hospital, Hanyang University College of Medicine, Seoul 04763, Korea.
Johanna Inhyang KimClinical Research Institute of Developmental Medicine, Hanyang University Hospital, Seoul 04763, Korea.ORCID 0000-0002-2367-0934
Hyun-Kyung ParkDepartment of Pediatrics, Hanyang University Hospital, Hanyang University College of Medicine, Seoul 04763, Korea.ORCID 0000-0001-5956-9208
Bung-Nyun KimDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Seoul National University Hospital, Seoul 03080, Korea.ORCID 0000-0002-2403-3291
Hyun Ju LeeDepartment of Pediatrics, Hanyang University Hospital, Hanyang University College of Medicine, Seoul 04763, Korea.ORCID 0000-0002-9110-2963
Hanyang University Seoul Hospital · KRBiostatistical Consulting (United States) · USSeoul National University Hospital · KR

Funding

Bio & Medical Technology Development Program of the National Research Foundation (NRF) funded by the Korean Government (MSIT) 2020M3E5D9080787, 2020R1F1A1048529 and 2019M3E5D1A01069345
6 · The paper itself

Abstract

Neurodevelopmental disorder (NDD) in preterm infants has become of great interest. We aimed to investigate the impact of preterm birth on the proportion of NDD using nationwide data provided by the Korean National Health Insurance Service. We included 4894 extremely preterm or extremely low-birth-weight (EP/ELBW; <28 weeks of gestation or birth weight < 1000 g) infants, 70,583 other preterm or low-birth-weight (OP/LBW; 28−36 weeks of gestation or birth weight < 2500 g) infants, and 264,057 full-term infants born between 2008 and 2015. We observed their neurodevelopment until 6 years of age or until the year 2019, whichever occurred first. Diagnoses of NDDs were based on the World Health Organization’s International Classification of Diseases 10th revision. An association between preterm birth and NDD was assessed using a multivariable logistic regression model. There was a stepwise increase in the risk of overall NDD with increasing degree of prematurity, from OP/LBW (adjusted odds ratio 4.46; 95% confidence interval 4.34−4.58), to EP/ELBW (16.15; 15.21−17.15). The EP/ELBW group was strongly associated with developmental delay (21.47; 20.05−22.99), cerebral palsy (88.11; 79.89−97.19), and autism spectrum disorder (11.64; 10.37−13.06). Preterm birth considerably increased the risk of NDD by the degree of prematurity.

Indexed as

autism spectrum disorderdevelopmental delaynationwide cohortneurodevelopmental disorderpreterm birth

Identifiers

PMID35566601
PMCPMC9099635
OpenAlexW4226078581

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.