ArticleJournal of clinical medicine2022
Association between Metabolically Healthy Obesity and Subclinical Atherosclerosis in the Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) Cohort.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Unmasking the role of hypertension in atherosclerosis among patients with obesity: a cardiometabolic dysfunction perspective.International journal of obesity (2005) · 2026Observational
- Clinical characterization of individuals with obesity but normal blood pressure and heart function - a descriptive study from the SCAPIS cohort.BMC cardiovascular disorders · 2026Article
- Obesity-Driven Segment-Specific Cerebrovascular Remodeling: A 3D High-Resolution Vessel Wall Imaging Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Association of novel metabolic status with asymptomatic intracranial arterial stenosis: A cross-sectional study.International journal of obesity (2005) · 2025Article
- Assessing metabolic health in a general population: A comparative analysis of three definitions in the Tromsø Study 2015-2016.PloS one · 2025Article
- Cardiovascular disease among bariatric surgery candidates: coronary artery screening and the impact of metabolic syndrome.Diabetology & metabolic syndrome · 2024Article
- Metabolically Healthy Obesity and Carotid Plaque among Steelworkers in North China: The Role of Inflammation.Nutrients · 2022Article
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Authors and funding
10 authors at 3 institutions in 1 country.
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Abstract
We aimed to investigate the association between a new definition of metabolic health (MH) and subclinical atherosclerosis in a cohort of patients without previous cardiovascular disease (CVD). In total, 7824 community-dwelling adults were categorized as normal weight, overweight, or obese. Metabolically healthy obesity (MHO) was defined as obesity accompanied by all of the following criteria: systolic blood pressure (BP) < 130 mmHg, no use of BP-lowering medication, waist-hip ratio <0.832 (women) and <0.887 (men), and no prevalent diabetes. Carotid atherosclerosis was defined as carotid plaque or mean carotid intima-media thickness ≥ 1.1 mm. The prevalence of carotid atherosclerosis was 8.3% and 1113 (14.2%) patients were classified as having MHO. All individuals classified as metabolically unhealthy were at an increased risk of carotid atherosclerosis independent of body mass index categories. Conversely, the risk of carotid atherosclerosis in individuals with MHO was not significantly increased compared to that in metabolically healthy normal weight participants (hazard ratio 1.20, 95% confidence interval 0.87−1.67). This new definition of MH was able to identify people with MHO without an increased risk of CVD in an Asian community cohort.
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