Evidence map›Paper›PMID 35566549›Full record

ArticleJournal of clinical medicine2022

Nutritional and Functional Impact of Acute SARS-CoV-2 Infection in Hospitalized Patients.

Angie Gómez-Uranga, Javier Guzmán-Martínez, Pedro Jesús Esteve-Atiénzar, Philip Wikman-Jorgensen, Juan Manuel Núñez-Cruz, Leticia Espinosa-Del-Barrio, Isidro Hernández-Isasi, Francisco J Pomares-Gómez, Eva Perelló-Camacho, Nuria Fernández-García and 2 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angie Gómez-UrangaInternal Medicine Service, University Hospital San Juan de Alicante, 03550 Alicante, Spain.ORCID 0000-0002-8503-2540
Javier Guzmán-MartínezInternal Medicine Service, University Hospital San Juan de Alicante, 03550 Alicante, Spain.ORCID 0000-0002-6526-5873
Pedro Jesús Esteve-AtiénzarInternal Medicine Service, University Hospital San Juan de Alicante, 03550 Alicante, Spain.ORCID 0000-0003-3043-3950
Philip Wikman-JorgensenInternal Medicine Service, University Hospital San Juan de Alicante, 03550 Alicante, Spain.
Juan Manuel Núñez-CruzInternal Medicine Service, University Hospital San Juan de Alicante, 03550 Alicante, Spain.
Leticia Espinosa-Del-BarrioInternal Medicine Service, University Hospital San Juan de Alicante, 03550 Alicante, Spain.
Isidro Hernández-IsasiInternal Medicine Service, University Hospital San Juan de Alicante, 03550 Alicante, Spain.
Francisco J Pomares-GómezFoundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain.
Eva Perelló-CamachoFoundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain.ORCID 0000-0001-6378-7566
Nuria Fernández-GarcíaFoundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain.ORCID 0000-0002-2096-4451
Ángel Sánchez-MirallesFoundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), 46020 Valencia, Spain.ORCID 0000-0002-8331-1554
Vicente Giner-GalvañInternal Medicine Service, University Hospital San Juan de Alicante, 03550 Alicante, Spain.ORCID 0000-0002-0999-9442

Funding

Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana 1,000Society of Internal Medicine of the Valencian Community 3,000
6 · The paper itself

Abstract

Aim: To assess the prevalence of malnutrition, frailty, and sarcopenia and the relationships between them in patients hospitalized for COVID-19. Methods: This was a cross-sectional study of the prevalence, determinants, and associations between malnutrition (GLIM 2019 criteria), sarcopenia (SARC-F scale, dynamometry, and calf circumference), and frailty (FRAIL scale) upon discharge following hospitalization for COVID 19. Results: A total of 101 patients (67.3% men, mean age 66.3 years) were recruited. Malnutrition was diagnosed in 49.5%, sarcopenia in 32.7%, and frailty in 28.7% of patients. Of the patients with malnutrition, 48% were also sarcopenic, and 42% were frail. There was a significant association between malnutrition and the severity of pneumonia according to the CURB-65 scale (odds ratio [OR] 2.61, p = 0.036), between sarcopenia and a Barthel score lower than 60 points (OR 29.52, p < 0.001), and between frailty and both a Barthel score lower than 60 points (OR 32.27, p < 0.001) and a length of hospital stay of over 30 days (OR 9.11, p = 0.008). Conclusions: Malnutrition, sarcopenia, and frailty are prevalent and interrelated entities in patients hospitalized for acute SARS CoV-2 infection, especially in patients with greater baseline functional impairment prior to admission and a higher infection severity.

Indexed as

frailtymalnutritionsarcopeniaSARS-CoV-2

Identifiers

PMID35566549
PMCPMC9103467

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.