Evidence map›Paper›PMID 35566537›Full record

ReviewJournal of clinical medicine2022

The Association between Vision Impairment and Depression: A Systematic Review of Population-Based Studies.

Gianni Virgili, Mariacristina Parravano, Davide Petri, Erica Maurutto, Francesca Menchini, Paolo Lanzetta, Monica Varano, Silvio Paolo Mariotti, Antonio Cherubini, Ersilia Lucenteforte

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. The Evolving Landscape of Vision Rehabilitation: Current Status and Future Directions.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Review
  3. Observational
  4. Article
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  11. Paralympic health: emerging trends and innovations.Frontiers in sports and active living · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Gianni VirgiliDepartment of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence and AOU Careggi, 50139 Florence, Italy.
Mariacristina ParravanoIRCCS-Fondazione Bietti, 00198 Rome, Italy.
Davide PetriDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-3690-4007
Erica MauruttoDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.
Francesca MenchiniDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.
Paolo LanzettaDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.ORCID 0000-0003-3746-141X
Monica VaranoIRCCS-Fondazione Bietti, 00198 Rome, Italy.
Silvio Paolo MariottiNCD Department, World Health Organization, 1211 Geneva, Switzerland.
Antonio CherubiniGeriatria, Accettazione Geriatrica e Centro di Ricerca per L'invecchiamento IRCCS INRCA, 60124 Ancona, Italy.
Ersilia LucenteforteDepartment of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-5608-5902
Fondazione G.B. Bietti · ITUniversity of Udine · ITUniversity of Pisa · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITWorld Health Organization · CH

Funding

Italian Ministry of Health RCR-2019-23669121_001World Health Organization 001
6 · The paper itself

Abstract

We conducted a systematic review and meta-analysis to investigate whether depression is associated with vision impairment (VI) in population-based studies in adults. MEDLINE and EMBASE were searched, from inception to June 2020. Studies were included if they provided two-by-two data for calculating the OR of association between VI and depression, or crude and/or an adjusted odds ratio (OR) with a corresponding 95% confidence interval (CI) were reported. The proportion of VI and depression was also extracted. ORs were pooled using random-effect models, proportions were pooled using random intercepts logistic regression models. Overall, 29 articles (31 studies) were included: of those, 18 studies used survey data (622,312 participants), 10 used clinical examination data (69,178 participants), and 3 used administrative databases (48,162,290 participants). The proportion of depression (95%CI) was 0.17 (0.13-0.22) overall and 0.27 (0.21-0.33) in VI subjects. The proportion of VI was 0.10 (0.07-0.16) overall and 0.20 (0.13-0.29) in depressed subjects. The association between VI and depression was direct: crude ORs were 1.89 (1.51-2.37) for survey data, 2.17 (1.76-2.67) for clinical examination data, and 3.34 (1.01-11.11) for administrative databases; adjusted ORs were 1.75 (1.34-2.30), 1.59 (1.22-1.96), and 2.47 (0.97-6.33), respectively. In conclusion, VI and depression are prevalent morbidities and should be actively sought when either is identified, especially in older adults.

Indexed as

blindnessdepressionmeta-analysissystematic reviewvisual impairment

Identifiers

PMID35566537
PMCPMC9103717
OpenAlexW4224736650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.