Evidence map›Paper›PMID 35566492›Full record

ReviewJournal of clinical medicine2022

Medical, Endoscopic and Surgical Management of Stricturing Crohn's Disease: Current Clinical Practice.

Fotios S Fousekis, Ioannis V Mitselos, Kostas Tepelenis, George Pappas-Gogos, Konstantinos H Katsanos, Georgios D Lianos, Francesco Frattini, Konstantinos Vlachos, Dimitrios K Christodoulou

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Stricturing Diseases of the Gastrointestinal Tract-Current Clinical Practice.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fotios S FousekisDepartment of Gastroenterology and Hepatology, University Hospital of Ioannina, University of Ioannina, 45110 Ioannina, Greece.
Ioannis V MitselosDepartment of Gastroenterology and Hepatology, University Hospital of Ioannina, University of Ioannina, 45110 Ioannina, Greece.
Kostas TepelenisDepartment of Surgery, University Hospital of Ioannina, University of Ioannina, 45110 Ioannina, Greece.
George Pappas-GogosDepartment of Surgery, University Hospital of Ioannina, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0001-5227-9806
Konstantinos H KatsanosDepartment of Gastroenterology and Hepatology, University Hospital of Ioannina, University of Ioannina, 45110 Ioannina, Greece.
Georgios D LianosDepartment of Surgery, University Hospital of Ioannina, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0002-6106-8178
Francesco FrattiniDepartment of Surgery, ASST Settelaghi, 21100 Varese, Italy.ORCID 0000-0002-0601-1048
Konstantinos VlachosDepartment of Surgery, University Hospital of Ioannina, University of Ioannina, 45110 Ioannina, Greece.
Dimitrios K ChristodoulouDepartment of Gastroenterology and Hepatology, University Hospital of Ioannina, University of Ioannina, 45110 Ioannina, Greece.ORCID 0000-0001-9694-1160
University of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of fibrostenotic intestinal disease occurs in approximately one-third of patients with Crohn's disease and is associated with increased morbidity. Despite introducing new biologic agents, stricturing Crohn's disease remains a significant clinical challenge. Medical treatment is considered the first-line treatment for inflammatory strictures, and anti-TNF agents appear to provide the most considerable benefit among the available medical treatments. However, medical therapy is ineffective on strictures with a mainly fibrotic component, and a high proportion of patients under anti-TNF will require surgery. In fibrotic strictures or cases refractory to medical treatment, an endoscopic or surgical approach should be considered depending on the location, length, and severity of the stricture. Both endoscopic balloon dilatation and endoscopic stricturoplasty are minimally invasive and safe, associated with a small risk of complications. On the other hand, the surgical approach is indicated in patients not suitable for endoscopic therapy. This review aimed to present and analyze the currently available medical, endoscopic, and surgical management of stricturing Crohn's disease.

Indexed as

anti-TNFCrohn’s diseaseendoscopic balloon dilatationstenosesstricturessurgery

Identifiers

PMID35566492
PMCPMC9104530
OpenAlexW4224218961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.