Evidence map›Paper›PMID 35566463›Full record

ArticleJournal of clinical medicine2022

Increased Complement-Associated Inflammation in Cytomegalovirus-Positive Hypertensive Anterior Uveitis Patients Based on the Aqueous Humor Proteomics Analysis.

Jin A Choi, Hyun-Hee Ju, Jiyoung Lee, Ju-Eun Kim, Soon-Young Paik, Nikolai P Skiba, Ponugoti Vasantha Rao

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. AHP DB: a reference database of proteins in the human aqueous humor.Database : the journal of biological databases and curation · 2024
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jin A ChoiDepartment of Ophthalmology, College of Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon 16247, Korea.
Hyun-Hee JuDepartment of Ophthalmology, College of Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon 16247, Korea.
Jiyoung LeeDepartment of Ophthalmology, College of Medicine, Daejon St. Mary's Hospital, The Catholic University of Korea, Daejon 34943, Korea.
Ju-Eun KimDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Soon-Young PaikDepartment of Microbiology, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0003-2748-6699
Nikolai P SkibaDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC 27710, USA.
Ponugoti Vasantha RaoDepartment of Ophthalmology, Duke University School of Medicine, Durham, NC 27710, USA.
Catholic University of Korea · KRDuke University · USThe Catholic University of Korea St. Vincent's Hospital · KR

Funding

VISION RESEARCHP30EY005722 · NEI · DUKE UNIVERSITY · PI Goldis Malek · 1985 to 2026
$19.3M
National Research Foundation of Korea NRF- 2022R1A2C1012677NEI NIH HHS P30 EY005722the St. Vincent's Hospital, Research Institute of Medical Science Foundation SVHR-2021-11
6 · The paper itself

Abstract

Herpetic anterior uveitis-associated ocular inflammation is commonly manifested with ocular hypertension and glaucoma. Relative to other viruses, cytomegalovirus (CMV) positive hypertensive anterior uveitis is associated with high recurrences of uveitis, as well as with uncontrolled intraocular pressure (IOP) and a subsequent higher requirement for future glaucoma surgery. To gain novel insights into the pathogenesis of ocular hypertension in these patients, we investigated the proteome changes of the aqueous humor (AH) derived from the CMV hypertensive anterior uveitis (CMV-HAU;

Indexed as

cytomegalovirusglaucomahypertensive anterior uveitisinflammationintraocular pressureuveitic glaucoma

Identifiers

PMID35566463
PMCPMC9101446
OpenAlexW4224284343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.