ArticleJournal of clinical medicine2022
The Role of Excessive Anticoagulation and Missing Hyperinflammation in ECMO-Associated Bleeding.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Association of anti-factor Xa-guided anticoagulation with hemorrhage during ECMO support: A systematic review and meta-analysis.Clinical cardiology · 2024Pooled it
- Flexible Bronchoscopy for Pulmonary Bleeding and Endobronchial Blood Clot Obstruction in Patients on Extra-Corporeal Membrane Oxygenation: A Case Series.Journal of clinical medicine · 2026Article
- Gastrointestinal bleeding in patients on venoarterial extracorporeal membrane oxygenation: a multicenter observational study.BMC gastroenterology · 2026Observational
- Vascular implications of non-pulsatile flow extracorporeal life support.Journal of cardiothoracic surgery · 2026Review
- Early impact of CytoSorb® adsorber on proinflammatory cytokine plasmatic levels in a porcine model of refractory cardiogenic shock supported with VA-ECMO.BMC cardiovascular disorders · 2025Article
- Alternative Anticoagulation for Patients with Heparin-Induced Thrombocytopenia on ECMO: A Narrative Review.Biomedicines · 2025Review
- Activated Clotting Time and Haemostatic Complications in Patients Receiving ECMO Support: A Systematic Review.Journal of cardiovascular development and disease · 2025Review
- The relationship between different anticoagulation monitoring indicators and heparin doses in adult patients with extracorporeal cardiopulmonary resuscitation.Frontiers in cardiovascular medicine · 2025Article
- Impact of bleeding and thrombosis on outcome of 945 COVID-19 VV-ECMO cases from a German registry.Frontiers in medicine · 2025Article
- Anticoagulation and associated complications in veno-arterial extracorporeal membrane oxygenation in adult patients: A systematic review and meta-analysis.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2024Review
- Mortality Predictors and Neurological Outcomes Following Extracorporeal Cardiopulmonary Resuscitation (eCPR): A Single-Center Retrospective Study.Journal of cardiovascular development and disease · 2024Article
- Clinical Application of Extracorporeal Membrane Oxygenation in the Treatment of Fulminant Myocarditis.Reviews in cardiovascular medicine · 2024Review
- Anaesthesiologic Considerations for Intraoperative ECMO Anticoagulation During Lung Transplantation: A Single-Centre, Retrospective, Observational Study.Transplant international : official journal of the European Society for Organ Transplantation · 2024Observational
- ECMO in Myocardial Infarction-Associated Cardiogenic Shock: Blood Biomarkers as Predictors of Mortality.Diagnostics (Basel, Switzerland) · 2023Article
- Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury.Brain sciences · 2023Review
- Association of aPTT-Guided Anticoagulation Monitoring with Thromboembolic Events in Patients Receiving V-A ECMO Support: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Article
- Thrombotic Events Develop in 1 Out of 5 Patients Receiving ECMO Support: An 11-Year Referral Centre Experience.Journal of clinical medicine · 2023Article
- ECMO in Cardiogenic Shock: Time Course of Blood Biomarkers and Associated Mortality.Diagnostics (Basel, Switzerland) · 2022Article
- ECMO Support in Refractory Cardiogenic Shock: Risk Factors for Mortality.Journal of clinical medicine · 2022Article
- Extracorporeal membrane oxygenation for cardiogenic shock: a meta-analysis of mortality and complications.Annals of intensive care · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracorporeal membrane oxygenation (ECMO) is increasingly used in carefully selected patients with cardiac or respiratory failure. However, complications are common and can be associated with worse outcomes, while data on risk factors and outcomes are inconsistent and sparse. Therefore, we sought to investigate potential risk factors and predictors of haemorrhage and adverse events during ECMO and its influence on mortality. We retrospectively reviewed all patients on ECMO support admitted to intensive care units of a tertiary university centre in Austria. In a period of ten years, ECMO support was used in 613 patients, with 321 patients meeting the inclusion criteria of this study. Haemorrhage, occurring in more than one third of the included patients (123, 38%), represented the most common and serious ECMO complication, being associated with an increased one year mortality (51% vs. 35%,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.