Evidence map›Paper›PMID 35566427›Full record

ArticleJournal of clinical medicine2022

Resting State Functional Connectivity between Dorsal Attentional Network and Right Inferior Frontal Gyrus in Concussed and Control Adolescents.

Stephen J Suss, Anna Manelis, Joao Paulo Lima Santos, Cynthia L Holland, Richelle S Stiffler, Hannah B Bitzer, Sarrah Mailliard, Madelyn Shaffer, Kaitlin Caviston, Michael W Collins and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Emotional Regulation and Adolescent Concussion: Overview and Role of Neuroimaging.International journal of environmental research and public health · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stephen J SussDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Anna ManelisDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0002-6605-5130
Joao Paulo Lima SantosDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0003-0676-8515
Cynthia L HollandUPMC Sports Medicine Concussion Program, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Richelle S StifflerDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Hannah B BitzerUPMC Sports Medicine Concussion Program, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Sarrah MailliardDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Madelyn ShafferUPMC Sports Medicine Concussion Program, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Kaitlin CavistonUPMC Sports Medicine Concussion Program, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Michael W CollinsUPMC Sports Medicine Concussion Program, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Mary L PhillipsDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Anthony P KontosUPMC Sports Medicine Concussion Program, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Amelia VersaceDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0001-9925-5203

Funding

Chuck Noll Foundation for Brain Injury Research FP00004146NIH HHS R01MH11488101
6 · The paper itself

Abstract

Concussion among adolescents continues to be a public health concern. Yet, the differences in brain function between adolescents with a recent concussion and adolescents with no history of concussion are not well understood. Although resting state functional magnetic resonance imaging (fMRI) can be a useful tool in examining these differences, few studies have used this technique to examine concussion in adolescents. Here, we investigate the differences in the resting state functional connectivity of 52 adolescents, 38 with a concussion in the previous 10 days (mean age = 15.6; female = 36.8%), and 14 controls with no concussion history (mean age = 15.1; female = 57.1%). Independent component analysis and dual regression revealed that control adolescents had significantly greater functional connectivity between the dorsal attention network (DAN) and right inferior frontal gyrus (RIFG) compared to concussed adolescents (p-corrected < 0.001). Specifically, there was a positive DAN-RIFG connectivity in control, but not concussed, adolescents. Our findings indicate that concussion is associated with disrupted DAN-RIFG connectivity, which may reflect a general, nonspecific response to injury.

Indexed as

adolescentsconcussiondorsal attention networkinferior frontal gyrusresting state functional connectivity

Identifiers

PMID35566427
PMCPMC9100070

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.