Evidence map›Paper›PMID 35566380›Full record

ArticleMolecules (Basel, Switzerland)2022

Effects of Two Natural Bisbenzylisoquinolines, Curine and Guattegaumerine, Extracted from

Jacques-Aurélien Sergent, Hilarion Mathouet, Christian Hulen, Pedro Lameiras, Marc Feuilloley, Abdelhakim Elomri, Nour-Eddine Lomri

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jacques-Aurélien SergentDepartment of Biology, UFR Sciences and Techniques, University of Cergy-Pontoise, 2 Ave A. Chauvin, 95302 Cergy-Pontoise, France.ORCID 0000-0002-1157-4099
Hilarion MathouetUNIROUEN, INSA Rouen, CNRS, COBRA (UMR 6014), Normandie University, 76000 Rouen, France.
Christian HulenBacterial Communication and Antimicrobial Strategies Research Unit, University of Rouen Normandy, 55 rue Saint Germain, 2700 Evreux, France.
Pedro LameirasUNIROUEN, INSA Rouen, CNRS, COBRA (UMR 6014), Normandie University, 76000 Rouen, France.ORCID 0000-0001-8416-750X
Marc FeuilloleyBacterial Communication and Antimicrobial Strategies Research Unit, University of Rouen Normandy, 55 rue Saint Germain, 2700 Evreux, France.ORCID 0000-0001-6467-4336
Abdelhakim ElomriUNIROUEN, INSA Rouen, CNRS, COBRA (UMR 6014), Normandie University, 76000 Rouen, France.ORCID 0000-0001-5026-5558
Nour-Eddine LomriDepartment of Biology, UFR Sciences and Techniques, University of Cergy-Pontoise, 2 Ave A. Chauvin, 95302 Cergy-Pontoise, France.
Centre National de la Recherche Scientifique · FRCY Cergy Paris Université · FRUniversité de Rouen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To develop new therapeutic molecules, it is essential to understand the biological effects and targets of clinically relevant compounds. In this article, we describe the extraction and characterization of two alkaloids from the roots of

Indexed as

ATP Binding Cassette Transporter, Subfamily B, Member 1BenzylisoquinolinesAnimalsATP Binding Cassette Transporter, Subfamily BGlycocholic AcidIsoquinolinesRatsRhodaminesVerapamilATP Binding Cassette Transporter, Subfamily BATP Binding Cassette Transporter, Subfamily B, Member 1BenzylisoquinolinescurineGlycocholic AcidguatteguamerineIsoquinolinesRhodaminesVerapamilalkaloidscurineefflux pump inhibitionguattegaumerineMDR1verapamil

Identifiers

PMID35566380
PMCPMC9099951
OpenAlexW4229457406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.