Evidence map›Paper›PMID 35566378›Full record

ArticleMolecules (Basel, Switzerland)2022

Exploring In Vitro Biological Cellular Responses of Pegylated β-Cyclodextrins.

Juliana Rincón-López, Miguelina Martínez-Aguilera, Patricia Guadarrama, Karla Juarez-Moreno, Yareli Rojas-Aguirre

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Juliana Rincón-LópezLaboratorio de Materiales Supramoleculares (SupraMatLab), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Circuito Exterior S/N, Ciudad Universitaria, Coyoacán 04510, Mexico.ORCID 0000-0002-5766-5631
Miguelina Martínez-AguileraLaboratorio de Materiales Supramoleculares (SupraMatLab), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Circuito Exterior S/N, Ciudad Universitaria, Coyoacán 04510, Mexico.ORCID 0000-0002-3570-6367
Patricia GuadarramaLaboratorio de Materiales Supramoleculares (SupraMatLab), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Circuito Exterior S/N, Ciudad Universitaria, Coyoacán 04510, Mexico.
Karla Juarez-MorenoCentro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México, (CFATA-UNAM), Blvd. Juriquilla #3001 Col. Jurica La Mesa CP, Querétaro 76230, Mexico.ORCID 0000-0002-6171-8601
Yareli Rojas-AguirreLaboratorio de Materiales Supramoleculares (SupraMatLab), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Circuito Exterior S/N, Ciudad Universitaria, Coyoacán 04510, Mexico.ORCID 0000-0001-5650-8637
Universidad Nacional Autónoma de México · MX

Funding

Consejo Nacional de Ciencia y Tecnología INFR-269071Consejo Nacional de Ciencia y Tecnología PN-2017-47-10Materials Research Institute-UNAM Mexico 1306Materials Research Institute-UNAM Mexico 1316National Autonomous University of Mexico PAPIIT- UNAM IA200821National Autonomous University of Mexico PAPIIT- UNAM IA200919National Autonomous University of Mexico PAPIIT-UNAM IN206919/32
6 · The paper itself

Abstract

βCDPEG5 and βCDPEG2 are two derivatives comprising seven PEG linear chains of 5 and 2 kDa, respectively, conjugated to βCD. As βCDPEGs display different physicochemical properties than their precursors, they could also trigger distinct cellular responses. To investigate the biological behavior of βCDPEGs in comparison to their parent compounds, we performed broad toxicological assays on RAW 264.7 macrophages, MC3T3-E1 osteoblasts, and MDCK cells. By analyzing ROS and NO

Indexed as

beta-CyclodextrinsMacrophagesOsteoblastsPolyethylene GlycolsReactive Oxygen Speciesbeta-CyclodextrinsPolyethylene GlycolsReactive Oxygen Speciescell cyclecell migrationcell viabilitymacrophagesMDCK cellsosteoblastspolyethylene glycolROSβ-cyclodextrin

Identifiers

PMID35566378
PMCPMC9101635
OpenAlexW4229367355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.