Evidence map›Paper›PMID 35566373›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis and In-Vivo Evaluation of Benzoxazole Derivatives as Promising Anti-Psoriatic Drugs for Clinical Use.

Rami Ayoub, Jamal Jilani, Qais Jarrar, Raad Alani, Chrismawan Ardianto, Khang Wen Goh, Dalia Ali, Said Moshawih

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Quercetin mediates the therapeutic effect ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rami AyoubDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman 11622, Jordan.
Jamal JilaniDepartment of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.
Qais JarrarDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman 11622, Jordan.
Raad AlaniDepartment of Physiotherapy, Faculty of Allied Medical Sciences, Isra University, Amman 11622, Jordan.
Chrismawan ArdiantoDepartment of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya 60115, Indonesia.ORCID 0000-0003-3713-7900
Khang Wen GohFaculty of Data Science and Information Technology, INTI International University, Nilai 71800, Malaysia.
Dalia AliDepartment of Physiotherapy, Faculty of Allied Medical Sciences, Isra University, Amman 11622, Jordan.ORCID 0000-0001-9680-0026
Said MoshawihPAP Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong BE1410, Brunei.ORCID 0000-0003-4840-0460

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2-(4-Chlorophenyl)-5-benzoxazoleacetic acid (CBA) and its ester, methyl-2-(4-chloro-phenyl)-5-benzoxazoleacetate (MCBA), were synthesized, and their structures were confirmed by

Indexed as

BenzoxazolesPsoriasisAnimalsDisease Models, AnimalImiquimodMiceMice, Inbred CBAPharmaceutical PreparationsSkinBenzoxazolesImiquimodPharmaceutical Preparationsarylbenzoxazoleimiquimodin vivoprodrugpsoriasissynthesis

Identifiers

PMID35566373
PMCPMC9104975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.