Evidence map›Paper›PMID 35566237›Full record

ArticleMolecules (Basel, Switzerland)2022

Increase in the Intracellular Bulk Water Content in the Early Phase of Cell Death of Keratinocytes, Corneoptosis, as Revealed by 65 GHz Near-Field CMOS Dielectric Sensor.

Keiichiro Shiraga, Yuichi Ogawa, Shojiro Kikuchi, Masayuki Amagai, Takeshi Matsui

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keiichiro ShiragaGraduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.ORCID 0000-0002-6139-9487
Yuichi OgawaGraduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.
Shojiro KikuchiInstitute for Advanced Medical Sciences, Hyogo College of Medicine, Nishinomiya 663-8501, Japan.
Masayuki AmagaiRIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.ORCID 0000-0003-3314-7052
Takeshi MatsuiRIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While bulk water and hydration water coexist in cells to support the expression of biological macromolecules, how the dynamics of water molecules, which have long been only a minor role in molecular biology research, relate to changes in cellular states such as cell death has hardly been explored so far due to the lack of evaluation techniques. In this study, we developed a high-precision measurement system that can discriminate bulk water content changes of ±0.02% (0.2 mg/cm

Indexed as

KeratinocytesWaterCell DeathEpidermisWaterbulk water contentcorneoptosisfluorescence imagingnear-field CMOS dielectric sensorSG1 cell

Identifiers

PMID35566237
PMCPMC9102150

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.