Evidence map›Paper›PMID 35566190›Full record

ArticleMolecules (Basel, Switzerland)2022

Estimating the Analytical Performance of Raman Spectroscopy for Quantification of Active Ingredients in Human

Hichem Kichou, Emilie Munnier, Yuri Dancik, Kamilia Kemel, Hugh J Byrne, Ali Tfayli, Dominique Bertrand, Martin Soucé, Igor Chourpa, Franck Bonnier

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Stratified quantification of targets in skin by three-dimensional Raman spectroscopic imaging.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Hichem KichouFaculté de Pharmacie, Université de Tours, EA6295 NMNS, NanoMédicaments et NanoSondes, 31 Avenue Monge, 37200 Tours, France.
Emilie MunnierFaculté de Pharmacie, Université de Tours, EA6295 NMNS, NanoMédicaments et NanoSondes, 31 Avenue Monge, 37200 Tours, France.ORCID 0000-0002-6691-4484
Yuri DancikFaculté de Pharmacie, Université de Tours, EA6295 NMNS, NanoMédicaments et NanoSondes, 31 Avenue Monge, 37200 Tours, France.
Kamilia KemelFaculté de Pharmacie, Université de Tours, EA6295 NMNS, NanoMédicaments et NanoSondes, 31 Avenue Monge, 37200 Tours, France.
Hugh J ByrneFOCAS Research Institute, TU Dublin, City Campus, Camden Row, D08 CKP1 Dublin 8, Ireland.ORCID 0000-0002-1735-8610
Ali TfayliFaculté de Pharmacie, Université Paris-Saclay, Lip(sys)2, Lipides, Systèmes Analytiques et Biologiques, 5 Rue Jean-Baptiste Clément, 92290 Châtenay-Malabry, France.
Dominique BertrandData_Frame, 25 Rue Stendhal, 44300 Nantes, France.
Martin SoucéFaculté de Pharmacie, Université de Tours, EA6295 NMNS, NanoMédicaments et NanoSondes, 31 Avenue Monge, 37200 Tours, France.ORCID 0000-0002-6627-9660
Igor ChourpaFaculté de Pharmacie, Université de Tours, EA6295 NMNS, NanoMédicaments et NanoSondes, 31 Avenue Monge, 37200 Tours, France.
Franck BonnierFaculté de Pharmacie, Université de Tours, EA6295 NMNS, NanoMédicaments et NanoSondes, 31 Avenue Monge, 37200 Tours, France.
Université de Tours · FRTechnological University Dublin · IEUniversité Paris-Saclay · FRUniversité Stendhal – Grenoble 3 · FR

Funding

APR-IR - Centre Val de Loire - project UFO 2020-00138875ARD Centre Val de Loire - Project MINIONs 2020-00141275
6 · The paper itself

Abstract

Confocal Raman microscopy (CRM) has become a versatile technique that can be applied routinely to monitor skin penetration of active molecules. In the present study, CRM coupled to multivariate analysis (namely PLSR-partial least squares regression) is used for the quantitative measurement of an active ingredient (AI) applied to isolated (ex vivo) human

Indexed as

EpidermisSpectrum Analysis, RamanHumansLeast-Squares AnalysisReproducibility of ResultsResorcinolsResorcinolsconfocal Raman spectroscopyhigh performance liquid chromatographyquantificationresorcinolstratum corneum

Identifiers

PMID35566190
PMCPMC9105701
OpenAlexW4225137490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.