Evidence map›Paper›PMID 35566141›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis and Investigation of the G-Quadruplex Binding Properties of Kynurenic Acid Derivatives with a Dihydroimidazoquinoline-3,5-dione Core.

Stefania Mazzini, Salvatore Princiotto, Loana Musso, Daniele Passarella, Giovanni Luca Beretta, Paola Perego, Sabrina Dallavalle

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. A CD Study of a Structure-Based Selection ofMolecules (Basel, Switzerland) · 2024
    Article
  2. Bioorganic Chemistry: Current and Future Perspectives.Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stefania MazziniDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-8220-0502
Salvatore PrinciottoDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0003-3440-8373
Loana MussoDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-6838-7753
Daniele PassarellaDepartment of Chemistry, University of Milan, 20133 Milan, Italy.ORCID 0000-0001-6180-9581
Giovanni Luca BerettaMolecular Pharmacology Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale Tumori, Via Amadeo 42, 20133 Milan, Italy.ORCID 0000-0002-5961-4109
Paola PeregoMolecular Pharmacology Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale Tumori, Via Amadeo 42, 20133 Milan, Italy.ORCID 0000-0003-2806-7269
Sabrina DallavalleDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-8813-8922
University of Milan · ITFondazione IRCCS Istituto Nazionale dei Tumori · IT

Funding

Ministry of Education, Universities and Research PRIN 2017 2017SA5837
6 · The paper itself

Abstract

G-quadruplexes are secondary structures originating from nucleic acid regions rich in guanines, which are well known for their involvement in gene transcription and regulation and DNA damage repair. In recent studies from our group, kynurenic acid (KYNA) derivative

Indexed as

G-QuadruplexesKynurenic AcidDNAHumansNitrogenTelomereDNAKynurenic AcidNitrogencytotoxicityDNAG-quadruplexKYNAkynurenic acidstabilization

Identifiers

PMID35566141
PMCPMC9103425
OpenAlexW4225016391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.