Evidence map›Paper›PMID 35566123›Full record

ReviewMolecules (Basel, Switzerland)2022

Plant Polysaccharides Modulate Immune Function via the Gut Microbiome and May Have Potential in COVID-19 Therapy.

Mengsheng Tang, Lu Cheng, Yanan Liu, Zufang Wu, Xin Zhang, Songmei Luo

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mengsheng TangDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.
Lu ChengDepartment of Food Science, Rutgers University, New Brunswick, NJ 08901, USA.
Yanan LiuDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.
Zufang WuDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.
Xin ZhangDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.ORCID 0000-0002-5795-9197
Songmei LuoDepartment of Pharmacy, Lishui Central Hospital, Lishui 323000, China.
Ningbo University · CNLishui Central Hospital · CNRutgers, The State University of New Jersey · US

Funding

Zhejiang Provincial Key Research and Development Program 2020C02037
6 · The paper itself

Abstract

Plant polysaccharides can increase the number and variety of beneficial bacteria in the gut and produce a variety of active substances, including short-chain fatty acids (SCFAs). Gut microbes and their specific metabolites have the effects of promoting anti-inflammatory activity, enhancing the intestinal barrier, and activating and regulating immune cells, which are beneficial for improving immunity. A strong immune system reduces inflammation caused by external viruses and other pathogens. Coronavirus disease 2019 (COVID-19) is still spreading globally, and patients with COVID-19 often have intestinal disease and weakened immune systems. This article mainly evaluates how polysaccharides in plants can improve the immune system barrier by improving the intestinal microecological balance, which may have potential in the prevention and treatment of COVID-19.

Indexed as

COVID-19 Drug TreatmentGastrointestinal MicrobiomeFatty Acids, VolatileHumansImmunityPolysaccharidesFatty Acids, VolatilePolysaccharidesCOVID-19gut floraimmunityplant polysaccharidesprobioticsSCFAs

Identifiers

PMID35566123
PMCPMC9101721
OpenAlexW4224952625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.