Evidence map›Paper›PMID 35566069›Full record

ArticleMolecules (Basel, Switzerland)2022

A Novel Mechanism for SIRT1 Activators That Does Not Rely on the Chemical Moiety Immediately C-Terminal to the Acetyl-Lysine of the Substrate.

Nian-Da Yu, Bing Wang, Xin-Zhu Li, Hao-Zhen Han, Dongxiang Liu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nian-Da YuCenter for Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Bing WangCenter for Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Xin-Zhu LiSchool of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID 0000-0002-9098-9590
Hao-Zhen HanCenter for Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Dongxiang LiuCenter for Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Chinese Academy of Sciences · CNNanjing University of Chinese Medicine · CN

Funding

National Natural Science Fundation of China 81973239 and 21672233
6 · The paper itself

Abstract

SIRT1, an NAD

Indexed as

Sirtuin 3SirtuinsCarbonLysineNADRiboseSirtuin 1Sirtuin 2CarbonLysineNADRiboseSirtuin 1Sirtuin 2Sirtuin 3Sirtuins2′-O-acetyl-ADP-riboseactivatorcovalent bonddeacetylaseSIRT1

Identifiers

PMID35566069
PMCPMC9099470
OpenAlexW4224315350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.