Evidence map›Paper›PMID 35566029›Full record

ArticleMolecules (Basel, Switzerland)2022

1,2,3-Triazolyl-tetrahydropyrimidine Conjugates as Potential Sterol Carrier Protein-2 Inhibitors: Larvicidal Activity against the Malaria Vector

Katharigatta N Venugopala, Pottathil Shinu, Christophe Tratrat, Pran Kishore Deb, Raquel M Gleiser, Sandeep Chandrashekharappa, Deepak Chopra, Mahesh Attimarad, Anroop B Nair, Nagaraja Sreeharsha and 7 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Silver-Catalyzed Cascade Cyclization of Amino-Molecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 7 countries.

Katharigatta N VenugopalaDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-0680-1549
Pottathil ShinuDepartment of Biomedical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-4245-0803
Christophe TratratDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0001-9064-1706
Pran Kishore DebDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Philadelphia University, Amman 19392, Jordan.ORCID 0000-0002-8650-2874
Raquel M GleiserCREAN-IMBIV (UNC-CONICET), Av. Valparaiso s.n. and FCEFyN, Universidad Nacional de Cordoba, AV. Sarsfield 299, Cordoba 5000, Argentina.ORCID 0000-0003-0726-2639
Sandeep ChandrashekharappaDepartment of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER-R) Raebareli, Lucknow, UP 226002, India.ORCID 0000-0003-2475-7270
Deepak ChopraDepartment of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal By-Pass Road, Bhauri, Bhopal, MP 462066, India.ORCID 0000-0002-0018-6007
Mahesh AttimaradDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-7007-9119
Anroop B NairDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-2850-8669
Nagaraja SreeharshaDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-2058-255X
Fawzi M MahomoodallyDepartment of Health Sciences, Faculty of Medicine and Health Science, University of Mauritius, Réduit 80837, Mauritius.ORCID 0000-0003-3962-8666
Michelyne HarounDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Mahmoud KandeelDepartment of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-3668-5147
Syed Mohammed Basheeruddin AsdaqDepartment of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Dariyah, Riyadh 13713, Saudi Arabia.ORCID 0000-0003-1533-9667
Viresh MohanlallDepartment of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban 4001, South Africa.ORCID 0000-0002-0103-7089
Nizar A Al-Shar'iDepartment of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.
Mohamed A MorsyDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-6752-9094
King Faisal University · SADurban University of Technology · ZAAlmaarefa UniversityConsejo Nacional de Investigaciones Científicas y Técnicas · ARIndian Institute of Science Education and Research, Bhopal · INJordan University of Science and Technology · JOKafrelsheikh University · EGNational Institute of Pharmaceutical Education and Research · INPhiladelphia University · JOUniversity of Mauritius · MU

Funding

Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia NA000107
6 · The paper itself

Abstract

Alteration of insect growth regulators by the action of inhibitors is becoming an attractive strategy to combat disease-transmitting insects. In the present study, we investigated the larvicidal effect of 1,2,3-triazolyl-pyrimidinone derivatives against the larvae of the mosquito

Indexed as

AnophelesInsecticidesMalariaAnimalsCarrier ProteinsJuvenile HormonesLarvaMolecular Docking SimulationMosquito ControlMosquito VectorsPyrimidinonesCarrier ProteinsInsecticidesJuvenile HormonesPyrimidinonessterol carrier proteinsAnopheles arabiensisBiginelli reactionclick chemistryin silico dockingmolecular hybridizationmosquito larvicidal activitypyrimidinesterol carrier protein-2triazole

Identifiers

PMID35566029
PMCPMC9102322
OpenAlexW4224321254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.