ArticleMolecules (Basel, Switzerland)2022
Rapid Detection of Five Estrogens Added Illegally to Dietary Supplements by Combining TLC with Raman Imaging Microscope.
Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Synthesis of molecularly imprinted polymers via core-shell magnetic mesoporous silicon-metal organic frameworks and their detection of three estrogens in traditional Chinese medicinal materials.Analytical and bioanalytical chemistry · 2026Article
- Preparation of deep eutectic solvent modified magnetic graphene oxide/metal organic framework nanocomposites for the extraction of three estrogens in cosmetics.Mikrochimica acta · 2024Article
- Decoding Cosmetic Complexities: A Comprehensive Guide to Matrix Composition and Pretreatment Technology.Molecules (Basel, Switzerland) · 2024Review
- Rapid Limit Test of Eight Quinolone Residues in Food Based on TLC-SERS, a New Limit Test Method.Molecules (Basel, Switzerland) · 2023Article
- Cucurbit[8]uril-mediated SERS plasmonic nanostructures with sub-nanometer gap for the identification and determination of estrogens.Mikrochimica acta · 2023Article
- Advances on Hormones in Cosmetics: Illegal Addition Status, Sample Preparation, and Detection Technology.Molecules (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Estrogens added illegally to dietary supplements are hazardous to human health. Traditional detection and analysis methods have many limitations, and we have developed an assay that combines thin-layer chromatography with Raman imaging microscopy (TLC-RIM). The five estrogens (estrone, estradiol, estriol, ethinyl estradiol, and diethylstilbestrol) were initially separated by TLC, then detected by area scanning Raman imaging with a 532 nm laser under a microscope. Raman spectra were obtained for each estrogen, which were used for detecting estrogen illegally added to botanical dietary supplements. The LOD of each estrogen was 0.4, 1.0, 0.8, 0.2, and 0.2 mg/mL, respectively. The matrix in the real sample did not interfere with the detection of estrogens. The method was fast, sensitive, stable, specific, and reliable.
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Registered trials
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