Evidence map›Paper›PMID 35566007›Full record

ArticleMolecules (Basel, Switzerland)2022

Structure-Based Bioisosterism Design, Synthesis, Biological Evaluation and In Silico Studies of Benzamide Analogs as Potential Anthelmintics.

Franco Vairoletti, Margot Paulino, Graciela Mahler, Gustavo Salinas, Cecilia Saiz

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Franco VairolettiLaboratorio de Química Farmacéutica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, Montevideo 11800, Uruguay.ORCID 0000-0002-5160-2250
Margot PaulinoLaBioFarMol, Departamento de Experimentación y Teoría de la Estructura de la Materia y sus Aplicaciones, Facultad de Química, Universidad de la República, Montevideo 11800, Uruguay.
Graciela MahlerLaboratorio de Química Farmacéutica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, Montevideo 11800, Uruguay.
Gustavo SalinasDepartamento de Biociencias, Facultad de Química, Universidad de la República, Montevideo 11800, Uruguay.ORCID 0000-0003-3350-3002
Cecilia SaizLaboratorio de Química Farmacéutica, Departamento de Química Orgánica, Facultad de Química, Universidad de la República, Montevideo 11800, Uruguay.ORCID 0000-0002-6451-1366

Funding

Agencia Nacional de Investigación e Innovación POS_NAC_2018_1_151488Comisión Sectorial de Investigación Científica (CSIC), UdelaR CSIC Grupos Química FarmacéuticaFOCEM - Fondo para la Convergencia Estructural del Mercosur COF 03/11PEDECIBA Uruguay
6 · The paper itself

Abstract

A recent screen of 67,012 compounds identified a new family of compounds with excellent nematicidal activity: the

Indexed as

AnthelminticsCaenorhabditis elegansAmidesAnimalsAntinematodal AgentsBenzamidesMammalsAmidesAnthelminticsAntinematodal AgentsbenzamideBenzamidesbioisosterismC. elegansE. granulosusnematicideortho-substituted benzamide

Identifiers

PMID35566007
PMCPMC9102753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.