Evidence map›Paper›PMID 35565987›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis, Experimental and Theoretical Study of Azidochromones.

Ena G Narváez-Ordoñez, Kevin A Pabón-Carcelén, Daniel A Zurita-Saltos, Pablo M Bonilla-Valladares, Trosky G Yánez-Darquea, Luis A Ramos-Guerrero, Sonia E Ulic, Jorge L Jios, Gustavo A Echeverría, Oscar E Piro and 3 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ena G Narváez-OrdoñezFacultad de Ciencias Químicas, Universidad Central del Ecuador, Francisco Viteri s/n y Gilberto Gato Sobral, Quito 170521, Ecuador.
Kevin A Pabón-CarcelénFacultad de Ciencias Químicas, Universidad Central del Ecuador, Francisco Viteri s/n y Gilberto Gato Sobral, Quito 170521, Ecuador.
Daniel A Zurita-SaltosFacultad de Ciencias Químicas, Universidad Central del Ecuador, Francisco Viteri s/n y Gilberto Gato Sobral, Quito 170521, Ecuador.
Pablo M Bonilla-ValladaresFacultad de Ciencias Químicas, Universidad Central del Ecuador, Francisco Viteri s/n y Gilberto Gato Sobral, Quito 170521, Ecuador.
Trosky G Yánez-DarqueaFacultad de Ciencias Químicas, Universidad Central del Ecuador, Francisco Viteri s/n y Gilberto Gato Sobral, Quito 170521, Ecuador.
Luis A Ramos-GuerreroCentro de Investigación de Alimentos CIAL, Universidad UTE, Quito 170527, Ecuador.ORCID 0000-0003-2654-3989
Sonia E UlicCEQUINOR (CONICET-UNLP), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Bv. 120 No 1465, La Plata 1900, Buenos Aires, Argentina.
Jorge L JiosLaboratorio UPL (UNLP-CIC), Camino Centenario e/505 y 508 (1897) M.B. Gonnet and Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, República Argentina. 47 esq. 115, La Plata 1900, Buenos Aires, Argentina.ORCID 0000-0001-7812-0043
Gustavo A EcheverríaDepartamento de Física, Facultad de Ciencias Exactas, Universidad Nacional de La Plata e IFLP (CONICET, CCT-La Plata), La Plata 1900, Buenos Aires, Argentina.ORCID 0000-0002-7139-6685
Oscar E PiroDepartamento de Física, Facultad de Ciencias Exactas, Universidad Nacional de La Plata e IFLP (CONICET, CCT-La Plata), La Plata 1900, Buenos Aires, Argentina.
Peter LangerInstitut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.
Christian D Alcívar-LeónFacultad de Ciencias Químicas, Universidad Central del Ecuador, Francisco Viteri s/n y Gilberto Gato Sobral, Quito 170521, Ecuador.ORCID 0000-0001-6987-3107
Jorge Heredia-MoyaCentro de Investigación Biomédica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170527, Ecuador.ORCID 0000-0001-7620-9140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 2-(haloalkyl)-3-azidomethyl and 6-azido chromones has been synthetized, characterized and studied by theoretical (DFT calculations) and spectroscopic methods (UV-Vis, NMR). The crystal structure of 3-azidomethyl-2-difluoromethyl chromone, determined by X-ray diffraction methods, shows a planar framework due to extended π-bond delocalization. Its molecular packing is stabilized by F···H, N···H and O···H hydrogen bonds, π···π stacking and C-O···π intermolecular interactions. Moreover, AIM, NCI and Hirshfeld analysis evidenced that azido moiety has a significant role in the stabilization of crystal packing through weak intermolecular interactions, where analysis of electronic density suggested closed-shell (CS) interatomic interactions.

Indexed as

Hydrogen BondingDensity Functional TheoryMagnetic Resonance SpectroscopyModels, MolecularX-Ray DiffractionazidochromoneHirshfeld surface analysisquantum chemical calculationsspectroscopic propertiesstructural X-ray diffraction

Identifiers

PMID35565987
PMCPMC9105743

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.