Evidence map›Paper›PMID 35565961›Full record

ArticleMolecules (Basel, Switzerland)2022

Anti-Inflammatory Effects of Cycloheterophyllin on Dinitrochlorobenzene-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice.

Chia-Chen Wang, Chien-Yu Hsiao, Yu-Jou Hsu, Horng-Huey Ko, Der-Chen Chang, Chi-Feng Hung

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Anti-Inflammatory Activity of Compounds Isolated fromInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Chia-Chen WangSchool of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Chien-Yu HsiaoDepartment of Nutrition and Health Science, Chang Guang University of Science and Technology, Taoyuan 33303, Taiwan.
Yu-Jou HsuPhD Program in Pharmaceutical Biotechnology, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Horng-Huey KoSchool of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Der-Chen ChangDepartment of Mathematics and Statistics and Department of Computer Science, Georgetown University, Washington, DC 20057, USA.
Chi-Feng HungSchool of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.ORCID 0000-0003-3478-5451
Fu Jen Catholic University · TWChang Gung University of Science and Technology · TWGeorgetown University · USKaohsiung Medical University · TW

Funding

Cardinal Tien Hospital Taiwan CTH-110A-FJU-2228; CTH111A-FJU-2226Chang Gung Memorial Hospital Taiwan CMRPF1J0042Ministry of Science and Technology Taiwan MOST110-2320-B-030 -004 -MY3
6 · The paper itself

Abstract

Atopic dermatitis (eczema) is a condition that makes skin red and itchy. Though common in children, the condition can occur at any age. Atopic dermatitis is persistent (chronic) and tends to recur periodically. It may be accompanied by asthma or hay fever. No cure has been found for eczema. Therefore, it is very important to develop ingredients that aid the prevention and treatment of atopic dermatitis. Cycloheterophyllin is derived from

Indexed as

Dermatitis, AtopicEczemaAnimalsAnti-Inflammatory AgentsCytokinesDinitrochlorobenzeneFlavonoidsHaCaT CellsHumansMiceMice, Inbred BALB CSkinAnti-Inflammatory AgentscycloheterophyllinCytokinesDinitrochlorobenzeneFlavonoidsArtocarpusatopic dermatitiscycloheterophyllinDNCBflavonekeratinocytesnatural product

Identifiers

PMID35565961
PMCPMC9099738
OpenAlexW4224215412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.