Evidence map›Paper›PMID 35565889›Full record

ArticleNutrients2022

L-Serine Supplementation Blunts Fasting-Induced Weight Regain by Increasing Brown Fat Thermogenesis.

Elena López-Gonzales, Lisa Lehmann, Francisco Javier Ruiz-Ojeda, René Hernández-Bautista, Irem Altun, Yasuhiro Onogi, Ahmed Elagamy Khalil, Xue Liu, Andreas Israel, Siegfried Ussar

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Elena López-GonzalesRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.
Lisa LehmannRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.
Francisco Javier Ruiz-OjedaRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.ORCID 0000-0002-4452-0855
René Hernández-BautistaRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.
Irem AltunRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.
Yasuhiro OnogiRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.ORCID 0000-0002-7950-8952
Ahmed Elagamy KhalilRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.
Xue LiuRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.ORCID 0000-0001-6585-964X
Andreas IsraelRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.
Siegfried UssarRG Adipocytes & Metabolism, Institute for Diabetes & Obesity, Helmholtz Center Munich, 85764 Munich, Germany.ORCID 0000-0001-7575-0920
Helmholtz Zentrum München · DEUniversidad de Granada · ES

Funding

Alexander von Humboldt Foundation Postdoctoral Fellowship
6 · The paper itself

Abstract

Weight regain after fasting, often exceeding the pre-fasting weight, is a common phenomenon and big problem for the treatment of obesity. Thus, novel interventions maintaining reduced body weight are critically important to prevent metabolic disease. Here we investigate the metabolic effects of dietary L-serine supplementation, known to modulate various organ functions. C57BL/6N-Rj male mice were supplemented with or without 1% L-serine in their drinking water and fed with a chow or high-fat diet. Mice were fed either

Indexed as

Adipose Tissue, BrownFastingAnimalsDietary SupplementsDiet, High-FatEnergy MetabolismMaleMiceMice, Inbred C57BLMice, Inbred StrainsObesitySerineThermogenesisWeight GainSerineBATbody weightenergy expenditurefastingL-serineobesityweight regain

Identifiers

PMID35565889
PMCPMC9104834
OpenAlexW4225369403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.