Evidence map›Paper›PMID 35565868›Full record

ArticleNutrients2022

Effects of a Formula with scGOS/lcFOS (9:1) and Glycomacropeptide (GMP) Supplementation on the Gut Microbiota of Very Preterm Infants.

Xue Yu, Yan Xing, Hui Liu, Yanmei Chang, Yanxia You, Yuqi Dou, Bin Liu, Qi Wang, Defu Ma, Lijun Chen and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xue YuSchool of Public Health, Peking University Health Science Center, Beijing 100191, China.
Yan XingDepartment of Pediatrics, Peking University Third Hospital, Beijing 100191, China.
Hui LiuDepartment of Pediatrics, Peking University Third Hospital, Beijing 100191, China.
Yanmei ChangDepartment of Pediatrics, Peking University Third Hospital, Beijing 100191, China.
Yanxia YouDepartment of Pediatrics, Peking University Third Hospital, Beijing 100191, China.
Yuqi DouSchool of Public Health, Peking University Health Science Center, Beijing 100191, China.
Bin LiuNational Engineering Center of Dairy for Maternal and Child Health, Beijing Sanyuan Foods Co., Ltd., Beijing 100163, China.
Qi WangCuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 730030, China.
Defu MaSchool of Public Health, Peking University Health Science Center, Beijing 100191, China.
Lijun ChenNational Engineering Center of Dairy for Maternal and Child Health, Beijing Sanyuan Foods Co., Ltd., Beijing 100163, China.
Xiaomei TongDepartment of Pediatrics, Peking University Third Hospital, Beijing 100191, China.

Funding

National Key Research and Development Program of China 2021YFC2700700Natural Science Foundation of Beijing NO. S160004Peking University Third Hospital Research Fund for outstanding overseas returnees No. BYSYLXHG2019005
6 · The paper itself

Abstract

Microbial colonization of very preterm (VPT) infants is detrimentally affected by the complex interplay of physiological, dietary, medical, and environmental factors. The aim of this study was to evaluate the effects of an infant formula containing the specific prebiotic mixture of scGOS/lcFOS (9:1) and glycomacropeptide (GMP) on the composition and function of VPT infants' gut microbiota. Metagenomic analysis was performed on the gut microbiota of VPT infants sampled at four time points: 24 h before the trial and 7, 14, and 28 days after the trial. Functional profiling was aggregated into gut and brain modules (GBMs) and gut metabolic modules (GMMs) based on the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.

Indexed as

Gastrointestinal MicrobiomeCaseinsFecesHumansInfantInfant FormulaInfant, NewbornInfant, PrematureOligosaccharidesPeptide FragmentsPrebioticscaseinomacropeptideCaseinsOligosaccharidesPeptide FragmentsPrebioticsglycomacropeptidemetagenomicsprebioticspreterm

Identifiers

PMID35565868
PMCPMC9102166

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.