Evidence map›Paper›PMID 35565867›Full record

ReviewNutrients2022

Vitamin D: Before, during and after Pregnancy: Effect on Neonates and Children.

José Luis Mansur, Beatriz Oliveri, Evangelina Giacoia, David Fusaro, Pablo René Costanzo

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 11 pooled it
22.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 11 syntheses or guidelines pooled it, 163 citations in OpenAlex.

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  12. Therapeutic effects of 1,25-dihydroxyvitamin DMolecular biology reports · 2026
    Article
  13. The Effects of Vitamin DAnimals : an open access journal from MDPI · 2026
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

José Luis MansurEndocrinology and Metabolism Center, La Plata B1902ADQ, Argentina.ORCID 0000-0002-8383-9543
Beatriz OliveriOsteoporosis and Metabolic Bone Diseases Laboratory, Institute of Immunology, Genetics, and Metabolism (INIGEM), School of Pharmacy and Biochemistry, Hospital de Clinicas, University of Buenos Aires, Mautalen, Health and Research, Buenos Aires C1053ABH, Argentina.
Evangelina GiacoiaEndocrinology Service Hospital Posadas, University of Buenos Aires, El Palomar C1053ABH, Argentina.ORCID 0000-0003-3694-8357
David FusaroBuenos Aires Gynecological Institute ACOG, Service Fundación Favaloro, Buenos Aires C1053ABH, Argentina.
Pablo René CostanzoAndrology Section, Endocrinology, Metabolism and Nuclear Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires PC C1199ABB, Argentina.ORCID 0000-0002-6130-2155
Universidad de Buenos Aires · ARFavaloro Foundation · ARHospital Italiano de Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A worldwide high prevalence of vitamin D (VD) deficiency has become of growing concern because of potential adverse effects on human health, including pregnant women and their offsprings. Beyond its classical function as a regulator of calcium and phosphate metabolism, together with its fundamental role in bone health in every stage of life, its deficiency has been associated to multiple adverse health effects. The classic effects of VD deficiency in pregnancy and neonates have been late hypocalcemia and nutritional rickets. Nevertheless, recent studies have linked VD to fertility and 25(OH)D with several clinical conditions in pregnancy: preeclampsia, gestational diabetes, higher incidence of cesarean section and preterm birth, while in infants, the clinical conditions are low birth weight, lower bone mass and possible relationship with the development of such diseases as bronchiolitis, asthma, type 1 diabetes, multiple sclerosis and autism included as VD non-classical actions. The supplementation with Vitamin D and achievement of optimal levels reduce maternal-fetal and newborn complications. Supplementation in children with VD deficiency reduces the risk of respiratory infections and possibly autoimmune diseases and autism. This review emphasizes the roles of Vitamin D deficiency and the consequences of intervention from preconception to infancy.

Indexed as

Pregnancy ComplicationsPremature BirthVitamin D DeficiencyCesarean SectionChildDietary SupplementsFemaleHumansInfantInfant, Low Birth WeightInfant, NewbornPregnancyVitamin DVitaminsVitamin DVitaminsfertilitypregnancyVitamin D

Identifiers

PMID35565867
PMCPMC9105305
OpenAlexW4225265692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.