Evidence map›Paper›PMID 35565864›Full record

ArticleNutrients2022

Gastric Mobility and Gastrointestinal Hormones in Older Patients with Sarcopenia.

Hsien-Hao Huang, Tse-Yao Wang, Shan-Fan Yao, Pei-Ying Lin, Julia Chia-Yu Chang, Li-Ning Peng, Liang-Kung Chen, David Hung-Tsang Yen

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hsien-Hao HuangDepartment of Emergency Medicine, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0002-0524-4093
Tse-Yao WangDepartment of Emergency Medicine, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0002-9660-2473
Shan-Fan YaoDepartment of Nuclear Medicine, Taipei Veterans General Hospital, Taipei 112201, Taiwan.
Pei-Ying LinDepartment of Emergency Medicine, Taipei Veterans General Hospital, Taipei 112201, Taiwan.
Julia Chia-Yu ChangDepartment of Emergency Medicine, Taipei Veterans General Hospital, Taipei 112201, Taiwan.
Li-Ning PengAging and Health Research Center, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Liang-Kung ChenAging and Health Research Center, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-2387-8508
David Hung-Tsang YenDepartment of Emergency Medicine, Taipei Veterans General Hospital, Taipei 112201, Taiwan.
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

intramural grants from Taipei Veterans General Hospital V108C-123, V111C-195Ministry of Science and Technology, Taiwan MOST107-2314-B-075-053 and MOST108-2314-B-075-034Veterans Affairs Council, Taiwan 107VACS-002, 108VACS-002, 109VACS-002, 110VACS-009Veterans General Hospitals and University System of Taiwan Joint Research Program VGHUST 110-G7-6-2
6 · The paper itself

Abstract

Sarcopenia has serious clinical consequences and poses a major threat to older people. Gastrointestinal environmental factors are believed to be the main cause. The aim of this study was to describe the relationship between sarcopenia and gastric mobility and to investigate the relationship between sarcopenia and the concentration of gastrointestinal hormones in older patients. Patients aged ≥ 75 years were recruited for this prospective study from August 2018 to February 2019 at the emergency department. The enrolled patients were tested for sarcopenia. Gastric emptying scintigraphy was conducted, and laboratory tests for cholecystokinin(CCK), glucagon-like peptide-1 (GLP-1), peptide YY (PYY), nesfatin, and ghrelin were performed during the fasting period. We enrolled 52 patients with mean age of 86.9 years, including 17 (32.7%) patients in the non-sarcopenia group, 17 (32.7%) patients in the pre-sarcopenia group, and 18 (34.6%) in the sarcopenia group. The mean gastric emptying half-time had no significant difference among three groups. The sarcopenia group had significantly higher fasting plasma concentrations of CCK, GLP-1, and PYY. We concluded that the older people with sarcopenia had significantly higher plasma concentrations of CCK, GLP-1, and PYY. In the elderly population, anorexigenic gastrointestinal hormones might have more important relationships with sarcopenia than orexigenic gastrointestinal hormones.

Indexed as

Gastrointestinal HormonesSarcopeniaAgedAged, 80 and overCholecystokininGastric EmptyingGhrelinGlucagon-Like Peptide 1HumansPeptide YYProspective StudiesCholecystokininGastrointestinal HormonesGhrelinGlucagon-Like Peptide 1Peptide YYgastric emptyinggastrointestinal hormonesolder patientssarcopenia

Identifiers

PMID35565864
PMCPMC9103579
OpenAlexW4225278550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.