Evidence map›Paper›PMID 35565853›Full record

ArticleNutrients2022

Biomarkers of Redox Balance Adjusted to Exercise Intensity as a Useful Tool to Identify Patients at Risk of Muscle Disease through Exercise Test.

Pierre-Edouard Grillet, Stéphanie Badiou, Karen Lambert, Thibault Sutra, Maëlle Plawecki, Eric Raynaud de Mauverger, Jean-Frédéric Brun, Jacques Mercier, Fares Gouzi, Jean-Paul Cristol

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Development and validation of a multiplexed LC-MS/MS ketone body assay for clinical diagnostics.Journal of mass spectrometry and advances in the clinical lab · 2024
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Pierre-Edouard GrilletPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.ORCID 0000-0002-5695-5020
Stéphanie BadiouPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.
Karen LambertPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.ORCID 0000-0002-6389-2451
Thibault SutraPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.
Maëlle PlaweckiPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.
Eric Raynaud de MauvergerPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.
Jean-Frédéric BrunPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.
Jacques MercierPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.
Fares GouziPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.
Jean-Paul CristolPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, CHU Montpellier, 34295 Montpellier, France.ORCID 0000-0001-8563-7278
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The screening of skeletal muscle diseases constitutes an unresolved challenge. Currently, exercise tests or plasmatic tests alone have shown limited performance in the screening of subjects with an increased risk of muscle oxidative metabolism impairment. Intensity-adjusted energy substrate levels of lactate (La), pyruvate (Pyr), β-hydroxybutyrate (BOH) and acetoacetate (AA) during a cardiopulmonary exercise test (CPET) could constitute alternative valid biomarkers to select "at-risk" patients, requiring the gold-standard diagnosis procedure through muscle biopsy. Thus, we aimed to test: (1) the validity of the V'O

Indexed as

Exercise TestMuscular DiseasesBiomarkersExerciseExercise ToleranceHumansMusclesOxidation-ReductionOxygen ConsumptionBiomarkerscardiopulmonary exercise test (CPET)exercise intoleranceLiquid Chromatography tandem Mass Spectrometry (LC-MS/MS)maximal oxygen uptakemetabolomicsmyopathytricarboxylic citric acid cycle

Identifiers

PMID35565853
PMCPMC9105000
OpenAlexW4225270021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.