Evidence map›Paper›PMID 35565806›Full record

ArticleNutrients2022

Prevalence of Sarcopenia in Women with Breast Cancer.

Delia Morlino, Maurizio Marra, Iolanda Cioffi, Lidia Santarpia, Pietro De Placido, Mario Giuliano, Carmine De Angelis, Simone Carrano, Annarita Verrazzo, Giuseppe Buono and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  6. Impact of sarcopenia on paclitaxel-induced peripheral neuropathy in early-stage breast cancer: a prospective observational study (the neuro-sarc study).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
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  18. The relationship between sarcopenia and serum irisin and TNF-α levels in newly diagnosed cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Delia MorlinoInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0002-3158-450X
Maurizio MarraInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0002-3258-7374
Iolanda CioffiInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0002-1408-209X
Lidia SantarpiaInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0003-2332-4836
Pietro De PlacidoOncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Mario GiulianoOncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Carmine De AngelisOncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Simone CarranoOncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Annarita VerrazzoOncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Giuseppe BuonoOncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Marianna NaccaratoInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Olivia Di VincenzoInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0003-3152-3130
Enza SperanzaInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0002-3241-1897
Sabino De PlacidoOncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Grazia ArpinoOncology Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
Fabrizio PasanisiInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0003-4224-7821
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcopenia is a common finding in patients with cancer and potentially influences the patient’s outcome. The aim of this study was to evaluate the prevalence of sarcopenia, according to the European Working Group on Sarcopenia in Older People, in a sample of women with breast cancer (BC) and a BMI lower than 30 kg/m2. This cross-sectional study was conducted in patients with BC, stage 0-III, and receiving therapy for BC; the women were recruited at the Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy. A control group with similar age and BMI was selected from the internal database. Anthropometry, bioimpedance analysis (BIA) and hand grip strength (HGS) were measured to detect sarcopenia. A total of 122 patients (mean age 49.3 ± 11.0 years, BMI 24.6 ± 3.0 kg/m2) and 80 healthy controls were analyzed. Sarcopenia was found in 13.9% patients with BC, while none of the subjects in the control group was sarcopenic. By comparing BC patients with and without sarcopenia and the control group, the fat-free mass of sarcopenic BC patients were significantly lower than those of both non-sarcopenic BC patients and the control (p < 0.05). The phase angle was also significantly lower in sarcopenic patients (−0.5 degrees, p = 0.048) than in the control group. Considering the prevalence of sarcopenia in patients with BC, our findings suggest the usefulness of body composition and HGS evaluation for early screening of sarcopenia to reduce the risk of associated complications.

Indexed as

Breast NeoplasmsSarcopeniaAdultAgedCross-Sectional StudiesFemaleHand StrengthHumansMiddle AgedPrevalencebioimpedance analysis (BIA)body compositionbreast cancerhand grip strength (HGS)phase angle (PhA)sarcopenia

Identifiers

PMID35565806
PMCPMC9099516
OpenAlexW4225158410

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.