Evidence map›Paper›PMID 35565759›Full record

ArticleNutrients2022

Anti-Hyperlipidemia, Hypoglycemic, and Hepatoprotective Impacts of Pearl Millet (

Nadiah S Alzahrani, Ghedeir M Alshammari, Afaf El-Ansary, Abu ElGasim A Yagoub, Musarat Amina, Ali Saleh, Mohammed Abdo Yahya

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07703371 (Impact of Dietary Fiber-Rich Kodo Millet Porridge Supplementation on Gut Microbiome and Metabolic Syndrome), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07703371 narecruitingnot on this mapstarted 2026, after this paper: background citation

Impact of Dietary Fiber-Rich Kodo Millet Porridge Supplementation on Gut Microbiome and Metabolic Syndrome

TypeinterventionalSponsorJSS MEDICAL COLLEGE, JSS ACADEMY OF HIGHER EDUCATION AND RESEARCHRan2026 to 2026Enrolled50ConditionsObesity & Overweight, Metabolic Syndrome, Gut Dysbiosis, Insulin ResistanceArmsKodo Millet Porridge Beverage
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Effects of fermentedFrontiers in pharmacology · 2024
    Article
  9. Millets as superfoods: Let thy cereal be thy medicine.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nadiah S AlzahraniDepartment of Food Science and Nutrition, College of Food Science and Agriculture, King Saud University, Riyadh 11451, Saudi Arabia.
Ghedeir M AlshammariDepartment of Food Science and Nutrition, College of Food Science and Agriculture, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-2043-1209
Afaf El-AnsaryCentral Research Laboratory, Female Campus, King Saud University, Riyadh 11472, Saudi Arabia.
Abu ElGasim A YagoubDepartment of Food Science and Nutrition, College of Food Science and Agriculture, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-6279-6361
Musarat AminaDepartment of Pharmacognosy, Pharmacy College, King Saud University, Riyadh 11451, Saudi Arabia.
Ali SalehDepartment of Food Science and Nutrition, College of Food Science and Agriculture, King Saud University, Riyadh 11451, Saudi Arabia.
Mohammed Abdo YahyaDepartment of Food Science and Nutrition, College of Food Science and Agriculture, King Saud University, Riyadh 11451, Saudi Arabia.
King Saud University · SA

Funding

Researchers Supporting Project, King Saud University, Riyadh, Saudi Arabia RSP-2021/84
6 · The paper itself

Abstract

This study tested the anti-hyperlipidemic, hypoglycemic, hepatoprotective, and anti-inflammatory effects of whole pearl millet grain powder (MPG) and its ethanol extract (MPGethaolE) in obese rats fed a high-fat diet. The rats were divided into eight groups based on the treatments they received: control, high fat diet (HFD), HFD + MGE (25 mg/Kg), HFD + MPGethaolE (50 mg/Kg), HFD + MPGethaolE (100 mg/Kg), HFD + MPG (10%), HFD + MPG (20%), and HFD + MPG (30%). The final body weight, visceral, epididymal fat pads, and the liver weight were significantly decreased, in a dose-dependent manner, in HFD fed rats that were co-administered either the MPG powder or MPGethaolE. In the same line, serum levels of triglycerides (TGs), cholesterol (CHOL), and low-density lipoprotein-cholesterol (LDL-c), as well as fasting glucose, insulin, HOMA-IR, and serum levels of lipopolysaccharides (LPS), interleukine-6 (IL-6), interleukine-10 (IL-10), C-reactive protein (CRP), tumor necrosis factor (TNF-α), and adiponectin were progressively decreased while serum levels of high-density lipoproteins (HDL-c) were significantly increased when increasing the doses of both treatments. In conclusion, both the raw powder and ethanolic extract of MP have a comparative dose-dependent anti-obesity, hypoglycemic, hypolipidemic, anti-inflammatory, and anti-steatotic in HFD-fed rats.

Indexed as

HyperlipidemiasPennisetumAnimalsCholesterolDiet, High-FatEthanolHypoglycemic AgentsObesityPlant ExtractsPowdersRatsCholesterolEthanolHypoglycemic AgentsPlant ExtractsPowdersethanol extracthepatoprotectionhyperlipidemiahypoglycemiainflammationPennisetum glaucum grains

Identifiers

PMID35565759
PMCPMC9105973
OpenAlexW4224939741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.