Evidence map›Paper›PMID 35565695›Full record

ReviewNutrients2022

Doubtful Justification of the Gluten-Free Diet in the Course of Hashimoto's Disease.

Małgorzata Szczuko, Anhelli Syrenicz, Katarzyna Szymkowiak, Aleksandra Przybylska, Urszula Szczuko, Jakub Pobłocki, Danuta Kulpa

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. The role of nutrition on thyroid health and disease: myths and facts.Journal of endocrinological investigation · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. The Role of Gluten in the Development of Autoimmune Thyroid Diseases: A Narrative Review.International journal of endocrinology and metabolism · 2024
    Review
  17. Review
  18. The Effects of Gluten on Weight Gain, Hematological, Biochemical, and Various Endocrinological Parameters.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Małgorzata SzczukoDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.ORCID 0000-0001-9808-0624
Anhelli SyreniczDepartment of Endocrinology, Metabolic Diseases and Internal Diseases, Pomeranian Medical University, 70-252 Szczecin, Poland.
Katarzyna SzymkowiakDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.
Aleksandra PrzybylskaDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, 60-834 Poznań, Poland.ORCID 0000-0002-5210-3277
Urszula SzczukoDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University, 71-460 Szczecin, Poland.ORCID 0000-0003-0610-7629
Jakub PobłockiDepartment of Endocrinology, Metabolic Diseases and Internal Diseases, Pomeranian Medical University, 70-252 Szczecin, Poland.
Danuta KulpaDepartment of Genetics, Plant Breeding and Biotechnology, Faculty of Environmental Management and Agriculture, West Pomeranian University of Technology, 71-434 Szczecin, Poland.ORCID 0000-0003-2352-7588
Pomeranian Medical University · PLPoznan University of Medical Sciences · PLWest Pomeranian University of Technology in Szczecin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The popularization of the gluten-free diet brings with it a fashion for its use, which can harm the treatment of Hashimoto's disease. The few studies in this regard do not confirm positive changes resulting from a gluten-free diet. At the same time, the presence of other comorbid autoimmune diseases in this group of patients is increasing. This may have important implications for the interpretation of test results and the need for a gluten-free diet in some patients. In this review, the PubMed database was searched for links between a gluten-free diet, Hashimoto's disease, and autoimmune diseases. When analyzing the available literature, we found no basis for introducing a gluten-free diet for the standard management of Hashimoto patients. The recommended diet is instead an anti-inflammatory diet that levels the supply (to compensate for deficiencies) of vitamin D, iodine, and selenium, which are found in plant products rich in polyphenols, antioxidants, and omega-3 fatty acids, as illustrated in this article.

Indexed as

Autoimmune DiseasesHashimoto DiseaseDiet, Gluten-FreeHumansVitamin DVitaminsVitamin DVitaminsanti-TGanti-TPOglutengluten-free dietHashimoto’s disease

Identifiers

PMID35565695
PMCPMC9101474
OpenAlexW4224312148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.