ArticleNutrients2022
The Association between Dietary Purine Intake and Mortality: Evidence from the CHNS Cohort Study.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association of serum biomarkers of dietary purine intake with glycaemic control and risk of preterm birth: two prospective cohort studies among pregnant women.EBioMedicine · 2026Article
- Dietary patterns and longitudinal frailty progression in older Chinese adults: a nationwide cohort study.The journal of nutrition, health & aging · 2026Article
- Exploring Environmental and Cardiometabolic Impacts Associated with Adherence to the Sustainable EAT-Lancet Reference Diet: Findings from the China Health and Nutrition Survey.Environmental health perspectives · 2025Article
- Association of Dietary Choline Intake With Incidence of Frailty: A Nationwide Prospective Cohort Study From China.Journal of cachexia, sarcopenia and muscle · 2025Article
- Effect on consumers' sustainable purchase intention of dietary supplement purine labeling.Frontiers in nutrition · 2025Article
- Association between 29 food groups of diet quality questionnaire and perceived stress in Chinese adults: a prospective study from China health and nutrition survey.BMC public health · 2024Article
- Dietary patterns associated with the incidence of hypertension among adult Japanese males: application of machine learning to a cohort study.European journal of nutrition · 2024Article
- Dietary branched-chain amino acids intake and new-onset hypertension: a nationwide prospective cohort study in China.Amino acids · 2024Article
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12 authors.
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Abstract
Objectives: To investigate the association between dietary purine intake and mortality among Chinese adults. Methods: Based on data from the 2004−2015 China Health and Nutrition Survey (CHNS) and the corresponding edition of China Food Composition, the average purine intake per day (mg/day) from 2004 to 2011 was calculated, and the surveyed population was divided into five groups by quintiles. The outcome event and timepoint of concern were defined as death and time, respectively, as reported by family members, recorded until the 2015 survey. Cox proportional hazards regression was used to estimate the hazard ratios (HRs) with 95% confidence intervals (CIs) for death. The possibly nonlinear relationship between purine intake and mortality was examined with restricted cubic splines. Results: We included 17,755 subjects, and the average purine intake among them was 355.07 ± 145.32 mg/day. Purine intake was inversely associated with mortality (Ptrend < 0.001). Compared with the lowest quintiles of purine intake, the highest quintiles (HR = 0.60; 95% CI: 0.46, 0.77) showed a significant association with lower mortality. The negative association with mortality was mainly found in plant-derived purine (Ptrend = 0.001) and, weakly, in animal-derived purine (Ptrend = 0.052). In addition, a U-shaped relationship between purine intake and mortality was observed in males; however, there was no statistically significant dose−response relationship in females. Conclusion: Considering the low-purine-intake levels of the Chinese population, we observed a U-shaped relationship between purine intake and mortality in males, but purine intake may not relate to mortality in females. Future studies should investigate the causal relationship between purine intake and disease burden in China.
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