Evidence map›Paper›PMID 35565669›Full record

Trial reportNutrients2022

Economic Evaluation of Individualized Nutritional Support for Hospitalized Patients with Chronic Heart Failure.

Philipp Schuetz, Suela Sulo, Stefan Walzer, Sebastian Krenberger, Zeno Stagna, Filomena Gomes, Beat Mueller, Cory Brunton

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Philipp SchuetzMedical University Department, Kantonsspital Aarau, 5001 Aarau, Switzerland.ORCID 0000-0001-6400-4949
Suela SuloAbbott Nutrition, Chicago, IL 60045, USA.
Stefan WalzerMArS Market Access & Pricing Strategy GmbH, 79576 Weil am Rhein, Germany.
Sebastian KrenbergerMArS Market Access & Pricing Strategy GmbH, 79576 Weil am Rhein, Germany.
Zeno StagnaDivision of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital, University of Bern, 4001 Bern, Switzerland.
Filomena GomesNOVA Medical School, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal.ORCID 0000-0003-1702-1433
Beat MuellerMedical University Department, Kantonsspital Aarau, 5001 Aarau, Switzerland.
Cory BruntonAbbott Nutrition, Chicago, IL 60045, USA.ORCID 0000-0002-3799-3742
Abbott (United States) · USUniversity of Basel · CHBaden-Wuerttemberg Cooperative State University · DEUniversidade Nova de Lisboa · PTUniversity of Bern · CH

Funding

Abbott Laboratories HA34
6 · The paper itself

Abstract

Background Malnutrition is a highly prevalent risk factor in hospitalized patients with chronic heart failure (CHF). A recent randomized trial found lower mortality and improved health outcomes when CHF patients with nutritional risk received individualized nutritional treatment. Objective To estimate the cost-effectiveness of individualized nutritional support in hospitalized patients with CHF. Methods This analysis used data from CHF patients at risk of malnutrition (N = 645) who were part of the Effect of Early Nutritional Therapy on Frailty, Functional Outcomes and Recovery of Undernourished Medical Inpatients Trial (EFFORT). Study patients with CHF were randomized into (i) an intervention group (individualized nutritional support to reach energy, protein, and micronutrient goals) or (ii) a control group (receiving standard hospital food). We used a Markov model with daily cycles (over a 6-month interval) to estimate hospital costs and health outcomes in the comparator groups, thus modeling cost-effectiveness ratios of nutritional interventions. Results With nutritional support, the modeled total additional cost over the 6-month interval was 15,159 Swiss Francs (SF). With an additional 5.77 life days, the overall incremental cost-effectiveness ratio for nutritional support vs. no nutritional support was 2625 SF per life day gained. In terms of complications, patients receiving nutritional support had a cost savings of 6214 SF and an additional 4.11 life days without complications, yielding an incremental cost-effectiveness ratio for avoided complications of 1513 SF per life day gained. Conclusions On the basis of a Markov model, this economic analysis found that in-hospital nutritional support for CHF patients increased life expectancy at an acceptable incremental cost-effectiveness ratio.

Indexed as

Heart FailureMalnutritionChronic DiseaseCost-Benefit AnalysisHumansNutritional Supportchronic heart failureclinical outcomescost savingseconomic analysisnutritional support

Identifiers

PMID35565669
PMCPMC9099480
OpenAlexW4225854363

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.