Evidence map›Paper›PMID 35565605›Full record

ArticleAnimals : an open access journal from MDPI2022

Ellagic Acid Improves Antioxidant Capacity and Intestinal Barrier Function of Heat-Stressed Broilers via Regulating Gut Microbiota.

Tai Yang, Bifan Liu, Yujie Wang, Xiangying Huang, Zhaoming Yan, Qian Jiang, Qinghua Chen

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  8. Review
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  10. Review
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  12. Ellagic Acid and Pomegranate (Aquaculture nutrition · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Effects of Heat-Induced Oxidative Stress and Astaxanthin on theCurrent issues in molecular biology · 2024
    Article
  17. Article
  18. Frontiers in microbiology · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tai YangHunan Co-Innovation Center of Animal Production Safety, Changsha 410128, China.
Bifan LiuCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Yujie WangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Xiangying HuangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Zhaoming YanCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-4629-6906
Qian JiangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-7840-0210
Qinghua ChenCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Hunan Agricultural University · CNHunan Vocational College of Safety Technology · CN

Funding

"Double first class" construction project of Hunan Agricultural University KXK201801004Science and technology projects of Changsha KQ1801017
6 · The paper itself

Abstract

Heat stress (HS) has been revealed to damage the antioxidant system and intestinal barrier function, which greatly threatens poultry production. The present study investigated the effects of dietary ellagic acid (EA) on the antioxidant system, gut barrier function, and gut microbiota of heat-stressed broilers. Arbor Acres 14-day-old broilers numbering 360 were randomly divided into six groups, including one negative control group (NC) and five experimental groups. The broilers in the NC group were supplemented with a basal diet at a normal temperature (23 ± 2 °C). The broilers in the experimental groups were supplemented with basal diets containing EA at different doses (0, 75, 150, 300, and 600 mg/kg) at HS temperature (35 ± 2 °C). The experiment lasted for 4 weeks. Results showed that dietary EA reduced the corticosterone (CORT), LPS, and diamine oxidase (DAO) levels in the serum of heat-stressed broilers. Additionally, dietary EA improved the antioxidant enzyme activity and mRNA levels of Nrf2/HO-1 in the ileum of heat-stressed broilers. The relative abundances of

Indexed as

antioxidant systembroilersellagic acidgrowth performanceheat stressintestinal barrier functionintestinal microbiota

Identifiers

PMID35565605
PMCPMC9131128
OpenAlexW4229044280

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.