Evidence map›Paper›PMID 35565465›Full record

ArticleCancers2022

Impact of Secretion-Active Osteoblast-Specific Factor 2 in Promoting Progression and Metastasis of Head and Neck Cancer.

Désirée Gül, Andrea Schweitzer, Aya Khamis, Shirley K Knauer, Guo-Bin Ding, Laura Freudelsperger, Ioannis Karampinis, Sebastian Strieth, Jan Hagemann, Roland H Stauber

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Désirée GülDepartment of Otorhinolaryngology, Head and Neck Surgery, Molecular and Cellular Oncology, University Medical Center, 55131 Mainz, Germany.ORCID 0000-0002-2446-5756
Andrea SchweitzerDepartment of Otorhinolaryngology, Head and Neck Surgery, Molecular and Cellular Oncology, University Medical Center, 55131 Mainz, Germany.
Aya KhamisDepartment of Otorhinolaryngology, Head and Neck Surgery, Molecular and Cellular Oncology, University Medical Center, 55131 Mainz, Germany.ORCID 0000-0001-5324-9932
Shirley K KnauerInstitute for Molecular Biology, Centre for Medical Biotechnology (ZMB), University Duisburg-Essen, Universitätsstraße, 45117 Essen, Germany.ORCID 0000-0003-4321-0924
Guo-Bin DingInstitute of Biotechnology, The Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, China.ORCID 0000-0002-3012-179X
Laura FreudelspergerDepartment of Otorhinolaryngology, Head and Neck Surgery, Molecular and Cellular Oncology, University Medical Center, 55131 Mainz, Germany.
Ioannis KarampinisAcademic Thoracic Center, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.ORCID 0000-0003-2742-9045
Sebastian StriethDepartment of Otorhinolaryngology, University Medical Center Bonn, 53127 Bonn, Germany.ORCID 0000-0003-0177-1926
Jan HagemannDepartment of Otorhinolaryngology, Head and Neck Surgery, Molecular and Cellular Oncology, University Medical Center, 55131 Mainz, Germany.ORCID 0000-0002-9846-7850
Roland H StauberDepartment of Otorhinolaryngology, Head and Neck Surgery, Molecular and Cellular Oncology, University Medical Center, 55131 Mainz, Germany.
Johannes Gutenberg University Mainz · DEShanxi University · CNUniversity of Duisburg-Essen · DE

Funding

DAAD/TransMed ST35Deutsche Forschungsgemeinschaft STR 1014; HA8065Else-Kröner Fresenius Foundation 2015_A233Stiftung Tumorforschung Kopf-Hals TF-OSF
6 · The paper itself

Abstract

Treatment success of head and neck cancer (HNC) is still hampered by tumor relapse due to metastases. Our study aimed to identify biomarkers by exploiting transcriptomics profiles of patient-matched metastases, primary tumors, and normal tissue mucosa as well as the

Indexed as

biomarkerHPVmetastasesmethylationoral cancerprotein secretiontherapy resistance

Identifiers

PMID35565465
PMCPMC9106029
OpenAlexW4229445340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.