Evidence map›Paper›PMID 35565405›Full record

ArticleCancers2022

Association of Rare Immune-Related Adverse Events to Survival in Advanced Cancer Patients Treated with Immune Checkpoint Inhibitors: A Real-World Single-Center Cohort Study.

Saara Kuusisalo, Jussi P Koivunen, Sanna Iivanainen

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Saara KuusisaloDepartment of Oncology and Radiotherapy, Oulu University Hospital and MRC Oulu, 90220 Oulu, Finland.
Jussi P KoivunenDepartment of Oncology and Radiotherapy, Oulu University Hospital and MRC Oulu, 90220 Oulu, Finland.
Sanna IivanainenDepartment of Oncology and Radiotherapy, Oulu University Hospital and MRC Oulu, 90220 Oulu, Finland.ORCID 0000-0003-1075-1134

Funding

Finnish Cancer Society NAOulu University NAThe Emil Aaltonen Foundation NAThe Finnish Medical Foundation NA
6 · The paper itself

Abstract

Immune checkpoint inhibitors (ICIs) are associated with immune-related (ir) adverse events (AEs) resembling autoimmune diseases. In this retrospective cohort study of patients (pts) treated with ICIs at Oulu University Hospital from 2014-2020, we analysed the spectrum of severe irAEs and their prognostic nature, focusing on rare irAEs. Pts (

Indexed as

autoimmunityimmune checkpoint inhibitorsimmune-related adverse eventprognosticsurvival

Identifiers

PMID35565405
PMCPMC9103509

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.