Evidence map›Paper›PMID 35565371›Full record

ArticleCancers2022

Development of an Image Analysis-Based Prognosis Score Using Google's Teachable Machine in Melanoma.

Stephan Forchhammer, Amar Abu-Ghazaleh, Gisela Metzler, Claus Garbe, Thomas Eigentler

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Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephan ForchhammerEberhardt Karls Universität, Universitäts-Hautklinik, 72076 Tübingen, Germany.ORCID 0000-0002-1274-2613
Amar Abu-GhazalehEberhardt Karls Universität, Universitäts-Hautklinik, 72076 Tübingen, Germany.
Gisela MetzlerZentrum für Dermatohistologie und Oralpathologie Tübingen/Würzburg, 72072 Tübingen, Germany.
Claus GarbeEberhardt Karls Universität, Universitäts-Hautklinik, 72076 Tübingen, Germany.ORCID 0000-0001-8530-780X
Thomas EigentlerDepartment of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Luisenstrasse 2, 10177 Berlin, Germany.ORCID 0000-0003-0019-2770

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increasing number of melanoma patients makes it necessary to establish new strategies for prognosis assessment to ensure follow-up care. Deep-learning-based image analysis of primary melanoma could be a future component of risk stratification.

objectivesTo develop a risk score for overall survival based on image analysis through artificial intelligence (AI) and validate it in a test cohort.

methodsHematoxylin and eosin (H&E) stained sections of 831 melanomas, diagnosed from 2012-2015 were photographed and used to perform deep-learning-based group classification. For this purpose, the freely available software of Google's teachable machine was used. Five hundred patient sections were used as the training cohort, and 331 sections served as the test cohort.

resultsUsing Google's Teachable Machine, a prognosis score for overall survival could be developed that achieved a statistically significant prognosis estimate with an AUC of 0.694 in a ROC analysis based solely on image sections of approximately 250 × 250 µm. The prognosis group "low-risk" (

conclusionsThe study supports the possibility of using deep learning-based classification systems for risk stratification in melanoma. The AI assessment used in this study provides a significant risk estimate in melanoma, but it does not considerably improve the existing risk classification based on the TNM classification.

Indexed as

artificial intelligencedeep learningGoogle’s teachable machinesmelanomaprognosisrisk score

Identifiers

PMID35565371
PMCPMC9105888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.