Evidence map›Paper›PMID 35565330›Full record

ArticleCancers2022

Management of Medial Sphenoid Wing Meningioma Involving the Cavernous Sinus: A Single-Center Series of 105 Cases.

Waseem Masalha, Dieter Henrik Heiland, Christine Steiert, Marie T Krüger, Daniel Schnell, Pamela Heiland, Marco Bissolo, Anca-L Grosu, Oliver Schnell, Jürgen Beck and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Waseem MasalhaDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0001-5581-8764
Dieter Henrik HeilandDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0002-9258-3033
Christine SteiertDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0002-5662-5777
Marie T KrügerDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0001-6142-5967
Daniel SchnellFaculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Pamela HeilandDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0002-7954-2974
Marco BissoloDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.
Anca-L GrosuFaculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Oliver SchnellDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.
Jürgen BeckDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.
Jürgen GrauvogelDepartment of Neurosurgery, Medical Centre-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0003-3330-3860
University of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMedial sphenoid wing meningiomas are among the three most common intracranial meningiomas. These tumors pose a challenge to neurosurgeons in terms of surgical treatment, as they may involve critical neurovascular structures and invade the cavernous sinus. In case of the latter, a complete resection may not be achievable. The purpose of this study was to investigate prognostic features affecting recurrence and progression-free survival (PFS) of medial sphenoid wing meningiomas involving the cavernous sinus, focusing on the contribution of surgery and postoperative radiotherapy.

methodsA retrospective analysis was conducted of the database of our institution, and 105 cases of medial sphenoid wing meningioma with invasion of the cavernous sinus, which were treated between 1998 and 2019, were included. Surgical treatment only was performed in 64 cases, and surgical treatment plus postoperative radiotherapy was performed in 41 cases. Kaplan-Meier analysis was conducted to estimate median survival and PFS rates, and Cox regression analysis was applied to determine significant factors that were associated with each therapeutic modality.

resultsThe risk of recurrence was significantly reduced after near-total resection (NTR) (

conclusionsMaximal safe resection and postoperative stereotactic radiotherapy significantly reduced the recurrence rate of medial sphenoid wing meningiomas with infiltration of the cavernous sinus.

Indexed as

cavernous sinusneurosurgerypostoperative radiotherapyprogression-free survivalsphenoid wing meningioma

Identifiers

PMID35565330
PMCPMC9102569
OpenAlexW4280551667

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.